Synergistic effect of (+)-pinitol from Saraca asoca with ß-lactam antibiotics and studies on the in silico possible mechanism.

Ahmad, Furkan; Misra, Laxminarain; Gupta, Vivek Kumar; Darokar, Mahendra Pandurang; Prakash, Om; Khan, Feroz; Shukla, Rakesh

Ahmad, Furkan; Misra, Laxminarain; Gupta, Vivek Kumar; Darokar, Mahendra Pandurang; Prakash, Om; Khan, Feroz; Shukla, Rakesh.

Affiliation

Ahmad F; a CSIR- Central Institute of Medicinal and Aromatic Plants , Lucknow 226015 , India.
Misra L; b Academy of Scientific and Innovative Research, CIMAP Campus , Lucknow 226015 , India.
Gupta VK; a CSIR- Central Institute of Medicinal and Aromatic Plants , Lucknow 226015 , India.
Darokar MP; a CSIR- Central Institute of Medicinal and Aromatic Plants , Lucknow 226015 , India.
Prakash O; a CSIR- Central Institute of Medicinal and Aromatic Plants , Lucknow 226015 , India.
Khan F; a CSIR- Central Institute of Medicinal and Aromatic Plants , Lucknow 226015 , India.
Shukla R; a CSIR- Central Institute of Medicinal and Aromatic Plants , Lucknow 226015 , India.

J Asian Nat Prod Res ; 18(2): 172-83, 2016.

Article in En | MEDLINE | ID: mdl-26527419

Subject(s)

Anti-Bacterial Agents/isolation & purification; Anti-Bacterial Agents/pharmacology; Anti-Inflammatory Agents/isolation & purification; Anti-Inflammatory Agents/pharmacology; Fabaceae/chemistry; Inositol/analogs & derivatives; beta-Lactams/isolation & purification; beta-Lactams/pharmacology; Animals; Anti-Bacterial Agents/chemistry; Anti-Inflammatory Agents/chemistry; Carrageenan/pharmacology; Chromatography, High Pressure Liquid; Edema/chemically induced; Edema/drug therapy; Female; Humans; India; Inositol/pharmacology; Lipopolysaccharides/pharmacology; Medicine, Ayurvedic; Methicillin-Resistant Staphylococcus aureus/drug effects; Microbial Sensitivity Tests; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Plant Bark/chemistry; Rats; Stereoisomerism; Tumor Necrosis Factor-alpha/antagonists & inhibitors; beta-Lactams/chemistry

Key words

(+)-pinitol; Caesalpiniaceae; Saraca asoca; in silico mechanism; synergistic antibiotic activity; ß-lactam antibiotics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Beta-Lactams / Inositol / Fabaceae / Anti-Inflammatory Agents / Anti-Bacterial Agents Type of study: Prognostic_studies Limits: Animals / Female / Humans Country/Region as subject: Asia Language: En Journal: J Asian Nat Prod Res Journal subject: BOTANICA / QUIMICA Year: 2016 Document type: Article Affiliation country: India Country of publication: United kingdom

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