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MITF and c-Jun antagonism interconnects melanoma dedifferentiation with pro-inflammatory cytokine responsiveness and myeloid cell recruitment.
Riesenberg, Stefanie; Groetchen, Angela; Siddaway, Robert; Bald, Tobias; Reinhardt, Julia; Smorra, Denise; Kohlmeyer, Judith; Renn, Marcel; Phung, Bengt; Aymans, Pia; Schmidt, Tobias; Hornung, Veit; Davidson, Irwin; Goding, Colin R; Jönsson, Göran; Landsberg, Jennifer; Tüting, Thomas; Hölzel, Michael.
Affiliation
  • Riesenberg S; Unit for RNA Biology, Institute for Clinical Chemistry and Clinical Pharmacology, University Hospital Bonn, Sigmund-Freud-Strasse 25, 53105 Bonn, Germany.
  • Groetchen A; Unit for RNA Biology, Institute for Clinical Chemistry and Clinical Pharmacology, University Hospital Bonn, Sigmund-Freud-Strasse 25, 53105 Bonn, Germany.
  • Siddaway R; Ludwig Institute for Cancer Research, Nuffield Department of Clinical Medicine, University of Oxford, Old Road Campus Research Building, Headington, Oxford OX3 7DQ, UK.
  • Bald T; Laboratory for Experimental Dermatology, Department of Dermatology, University Hospital Bonn, Sigmund-Freud-Strasse 25, 53105 Bonn, Germany.
  • Reinhardt J; Unit for RNA Biology, Institute for Clinical Chemistry and Clinical Pharmacology, University Hospital Bonn, Sigmund-Freud-Strasse 25, 53105 Bonn, Germany.
  • Smorra D; Unit for RNA Biology, Institute for Clinical Chemistry and Clinical Pharmacology, University Hospital Bonn, Sigmund-Freud-Strasse 25, 53105 Bonn, Germany.
  • Kohlmeyer J; Laboratory for Experimental Dermatology, Department of Dermatology, University Hospital Bonn, Sigmund-Freud-Strasse 25, 53105 Bonn, Germany.
  • Renn M; Laboratory for Experimental Dermatology, Department of Dermatology, University Hospital Bonn, Sigmund-Freud-Strasse 25, 53105 Bonn, Germany.
  • Phung B; Division of Oncology and Pathology, Department of Clinical Sciences, Lund University, Barngatan 2B, Lund 221 85, Sweden.
  • Aymans P; Laboratory for Experimental Dermatology, Department of Dermatology, University Hospital Bonn, Sigmund-Freud-Strasse 25, 53105 Bonn, Germany.
  • Schmidt T; Institute of Molecular Medicine, University Hospital, University of Bonn, Sigmund-Freud-Strasse 25, 53127 Bonn, Germany.
  • Hornung V; Institute of Molecular Medicine, University Hospital, University of Bonn, Sigmund-Freud-Strasse 25, 53127 Bonn, Germany.
  • Davidson I; Department of Functional Genomics and Cancer, Institut de Génétique et de Biologie Moléculaire et Cellulaire, CNRS/INSERM/ULP, 1 Rue Laurent Fries, Illkirch Cédex 67404, France.
  • Goding CR; Ludwig Institute for Cancer Research, Nuffield Department of Clinical Medicine, University of Oxford, Old Road Campus Research Building, Headington, Oxford OX3 7DQ, UK.
  • Jönsson G; Division of Oncology and Pathology, Department of Clinical Sciences, Lund University, Barngatan 2B, Lund 221 85, Sweden.
  • Landsberg J; Laboratory for Experimental Dermatology, Department of Dermatology, University Hospital Bonn, Sigmund-Freud-Strasse 25, 53105 Bonn, Germany.
  • Tüting T; Laboratory for Experimental Dermatology, Department of Dermatology, University Hospital Bonn, Sigmund-Freud-Strasse 25, 53105 Bonn, Germany.
  • Hölzel M; Unit for RNA Biology, Institute for Clinical Chemistry and Clinical Pharmacology, University Hospital Bonn, Sigmund-Freud-Strasse 25, 53105 Bonn, Germany.
Nat Commun ; 6: 8755, 2015 Nov 04.
Article in En | MEDLINE | ID: mdl-26530832
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Skin Neoplasms / Gene Expression Regulation, Neoplastic / Cytokines / Myeloid Cells / Microphthalmia-Associated Transcription Factor / Cell Dedifferentiation / Melanoma Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2015 Document type: Article Affiliation country: Germany Country of publication: United kingdom
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Skin Neoplasms / Gene Expression Regulation, Neoplastic / Cytokines / Myeloid Cells / Microphthalmia-Associated Transcription Factor / Cell Dedifferentiation / Melanoma Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2015 Document type: Article Affiliation country: Germany Country of publication: United kingdom