[1,4]-sigmatropic rearrangement of chiral nitrones and their utilization in the synthesis of new iminosugars.

Malinowski, Maciej; Rowicki, Tomasz; Guzik, Patrycja; Gryszel, Maciej; Lapczynski, Sebastian; Wielechowska, Monika; Czerwinska, Karolina; Madura, Izabela; Sas, Wojciech

Malinowski, Maciej; Rowicki, Tomasz; Guzik, Patrycja; Gryszel, Maciej; Lapczynski, Sebastian; Wielechowska, Monika; Czerwinska, Karolina; Madura, Izabela; Sas, Wojciech.

Affiliation

Malinowski M; Faculty of Chemistry, Warsaw University of Technology, ul. Noakowskiego 3, 00-664 Warsaw, Poland. tomek@ch.pw.edu.pl.

Org Biomol Chem ; 14(2): 470-482, 2016 Jan 14.

Article in En | MEDLINE | ID: mdl-26563609

Subject(s)

Enzyme Inhibitors/pharmacology; Glucosidases/antagonists & inhibitors; Imino Sugars/chemical synthesis; Imino Sugars/pharmacology; Nitrogen Oxides/chemistry; Cell Line, Tumor; Cell Proliferation/drug effects; Cell Survival/drug effects; Dose-Response Relationship, Drug; Enzyme Inhibitors/chemical synthesis; Enzyme Inhibitors/chemistry; Glucosidases/metabolism; Humans; Imino Sugars/chemistry; Models, Molecular; Molecular Structure; Quantum Theory; Stereoisomerism; Structure-Activity Relationship; Thermodynamics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Enzyme Inhibitors / Imino Sugars / Glucosidases / Nitrogen Oxides Limits: Humans Language: En Journal: Org Biomol Chem Journal subject: BIOQUIMICA / QUIMICA Year: 2016 Document type: Article Affiliation country: Poland Country of publication: United kingdom

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