Early development of the vertebral column.
Semin Cell Dev Biol
; 49: 83-91, 2016 Jan.
Article
in En
| MEDLINE
| ID: mdl-26564689
ABSTRACT
The segmental organization of the vertebrate body is most obviously visible in the vertebral column, which consists of a series of vertebral bones and interconnecting joints and ligaments. During embryogenesis, the vertebral column derives from the somites, which are the primary segments of the embryonic paraxial mesoderm. Anatomical, cellular and molecular aspects of vertebral column development have been of interest to developmental biologists for more than 150 years. This review briefly summarizes the present knowledge on early steps of vertebral column development in amniotes, starting from sclerotome formation and leading to the establishment of the anatomical bauplan of the spine composed of vertebral bodies, vertebral arches, intervertebral discs and ribs, and their specific axial identities along the body axis.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Spine
Limits:
Animals
/
Humans
Language:
En
Journal:
Semin Cell Dev Biol
Journal subject:
EMBRIOLOGIA
Year:
2016
Document type:
Article
Publication country:
ENGLAND
/
ESCOCIA
/
GB
/
GREAT BRITAIN
/
INGLATERRA
/
REINO UNIDO
/
SCOTLAND
/
UK
/
UNITED KINGDOM