Responsive neurostimulation in epilepsy.
Expert Rev Neurother
; 15(12): 1445-54, 2015.
Article
in En
| MEDLINE
| ID: mdl-26580843
ABSTRACT
Various neurostimulation modalities have emerged in the field of epilepsy. Despite the fact that delivery of an electrical current to the hyperexcitable epileptic brain might, at first, seem contradictory, neurostimulation has become an established therapeutic option with a promising efficacy and adverse effects profile. In "responsive" neurostimulation the strategy is to interfere as early as possible with the accumulation of seizure activity to prematurely abort or even prevent an upcoming seizure. The design of technology required for responsive stimulation is more challenging compared with devices for open-loop neurostimulation. The achievement of therapeutic success is dependent on adequate sensing and stimulation algorithms and a fast coupling between both. The benefits of delivering current only at the time of an approaching seizure merit further investigation. Current experience with responsive neurostimulation in epilepsy is still limited, but seems promising.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Deep Brain Stimulation
/
Epilepsy
Limits:
Humans
Language:
En
Journal:
Expert Rev Neurother
Journal subject:
NEUROLOGIA
/
TERAPEUTICA
Year:
2015
Document type:
Article
Affiliation country:
Belgium