Synthesis and biological evaluation of pyrazolopyrimidines  as potential antibacterial agents.

Goshu, Gashaw M; Ghose, Debarati; Bain, Joy M; Pierce, Phillip G; Begley, Darren W; Hewitt, Stephen N; Udell, Hannah S; Myler, Peter J; Meganathan, R; Hagen, Timothy J

Synthesis and biological evaluation of pyrazolopyrimidines as potential antibacterial agents.

Goshu, Gashaw M; Ghose, Debarati; Bain, Joy M; Pierce, Phillip G; Begley, Darren W; Hewitt, Stephen N; Udell, Hannah S; Myler, Peter J; Meganathan, R; Hagen, Timothy J.

Affiliation

Goshu GM; Department of Chemistry and Biochemistry, Northern Illinois University, 300 Normal Road, DeKalb, IL 60115, USA

Bioorg Med Chem Lett ; 25(24): 5699-704, 2015 Dec 15.

Article in En | MEDLINE | ID: mdl-26584881

Subject(s)

Anti-Bacterial Agents/chemical synthesis; Pyrazoles/chemistry; Pyridines/chemistry; Anti-Bacterial Agents/chemistry; Anti-Bacterial Agents/pharmacology; Burkholderia/drug effects; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Pseudomonas aeruginosa/drug effects; Pyrazoles/chemical synthesis; Pyrazoles/pharmacology; Pyridines/chemical synthesis; Pyridines/pharmacology; Structure-Activity Relationship

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrazoles / Pyridines / Anti-Bacterial Agents Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2015 Document type: Article Affiliation country: United States

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