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Trastuzumab emtansine (T-DM1) renders HER2+ breast cancer highly susceptible to CTLA-4/PD-1 blockade.
Müller, Philipp; Kreuzaler, Matthias; Khan, Tarik; Thommen, Daniela S; Martin, Kea; Glatz, Katharina; Savic, Spasenija; Harbeck, Nadia; Nitz, Ulrike; Gluz, Oleg; von Bergwelt-Baildon, Michael; Kreipe, Hans; Reddy, Sai; Christgen, Matthias; Zippelius, Alfred.
Affiliation
  • Müller P; Department of Biomedicine, University Hospital and University of Basel, CH-4031 Basel, Switzerland. ph.mueller@unibas.ch alfred.zippelius@usb.ch.
  • Kreuzaler M; Department of Biomedicine, University Hospital and University of Basel, CH-4031 Basel, Switzerland.
  • Khan T; Department of Biosystems Science and Engineering, ETH Zürich, CH-4058 Basel, Switzerland.
  • Thommen DS; Department of Biomedicine, University Hospital and University of Basel, CH-4031 Basel, Switzerland. Department of Medical Oncology, University Hospital Basel, CH-4031 Basel, Switzerland.
  • Martin K; Department of Biomedicine, University Hospital and University of Basel, CH-4031 Basel, Switzerland.
  • Glatz K; Institute of Pathology, University Hospital Basel, CH-4031 Basel, Switzerland.
  • Savic S; Institute of Pathology, University Hospital Basel, CH-4031 Basel, Switzerland.
  • Harbeck N; Breast Center, Department of Obstetrics and Gynecology, University of Munich, D-81377 Munich, Germany. West German Study Group, D-41061 Mönchengladbach, Germany.
  • Nitz U; West German Study Group, D-41061 Mönchengladbach, Germany. Women's Clinic, Heinrich Heine University Düsseldorf, D-40225 Düsseldorf, Germany. Breast Center Niederrhein, Ev. Bethesda Hospital, D-41061 Mönchengladbach, Germany.
  • Gluz O; West German Study Group, D-41061 Mönchengladbach, Germany. Breast Center Niederrhein, Ev. Bethesda Hospital, D-41061 Mönchengladbach, Germany.
  • von Bergwelt-Baildon M; First Department of Internal Medicine, University of Cologne, D-50937 Cologne, Germany.
  • Kreipe H; West German Study Group, D-41061 Mönchengladbach, Germany. Institute of Pathology, Hannover Medical School, D-30625 Hannover, Germany.
  • Reddy S; Department of Biosystems Science and Engineering, ETH Zürich, CH-4058 Basel, Switzerland.
  • Christgen M; West German Study Group, D-41061 Mönchengladbach, Germany. Institute of Pathology, Hannover Medical School, D-30625 Hannover, Germany.
  • Zippelius A; Department of Biomedicine, University Hospital and University of Basel, CH-4031 Basel, Switzerland. Department of Medical Oncology, University Hospital Basel, CH-4031 Basel, Switzerland. ph.mueller@unibas.ch alfred.zippelius@usb.ch.
Sci Transl Med ; 7(315): 315ra188, 2015 Nov 25.
Article in En | MEDLINE | ID: mdl-26606967
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Breast Neoplasms / Genes, erbB-2 / Antibodies, Monoclonal, Humanized / CTLA-4 Antigen / Programmed Cell Death 1 Receptor / Maytansine / Antineoplastic Agents Limits: Animals / Female / Humans Language: En Journal: Sci Transl Med Journal subject: CIENCIA / MEDICINA Year: 2015 Document type: Article Country of publication: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Breast Neoplasms / Genes, erbB-2 / Antibodies, Monoclonal, Humanized / CTLA-4 Antigen / Programmed Cell Death 1 Receptor / Maytansine / Antineoplastic Agents Limits: Animals / Female / Humans Language: En Journal: Sci Transl Med Journal subject: CIENCIA / MEDICINA Year: 2015 Document type: Article Country of publication: United States