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Recombinant Adeno Associated Viral (AAV) vector type 9 delivery of Ex1-Q138-mutant huntingtin in the rat striatum as a short-time model for in vivo studies in drug discovery.
Ceccarelli, Ilaria; Fiengo, Pasquale; Remelli, Rosaria; Miragliotta, Vincenzo; Rossini, Lara; Biotti, Irene; Cappelli, Alessandra; Petricca, Lara; La Rosa, Salvatore; Caricasole, Andrea; Pollio, Giuseppe; Scali, Carla.
Affiliation
  • Ceccarelli I; Siena Biotech S.p.A, Strada del Petriccio e Belriguardo, 35 53100 Siena, (Italy).
  • Fiengo P; Siena Biotech S.p.A, Strada del Petriccio e Belriguardo, 35 53100 Siena, (Italy).
  • Remelli R; Siena Biotech S.p.A, Strada del Petriccio e Belriguardo, 35 53100 Siena, (Italy).
  • Miragliotta V; Siena Biotech S.p.A, Strada del Petriccio e Belriguardo, 35 53100 Siena, (Italy).
  • Rossini L; Siena Biotech S.p.A, Strada del Petriccio e Belriguardo, 35 53100 Siena, (Italy).
  • Biotti I; Siena Biotech S.p.A, Strada del Petriccio e Belriguardo, 35 53100 Siena, (Italy).
  • Cappelli A; Siena Biotech S.p.A, Strada del Petriccio e Belriguardo, 35 53100 Siena, (Italy).
  • Petricca L; Siena Biotech S.p.A, Strada del Petriccio e Belriguardo, 35 53100 Siena, (Italy).
  • La Rosa S; Siena Biotech S.p.A, Strada del Petriccio e Belriguardo, 35 53100 Siena, (Italy).
  • Caricasole A; Siena Biotech S.p.A, Strada del Petriccio e Belriguardo, 35 53100 Siena, (Italy).
  • Pollio G; Siena Biotech S.p.A, Strada del Petriccio e Belriguardo, 35 53100 Siena, (Italy).
  • Scali C; Siena Biotech S.p.A, Strada del Petriccio e Belriguardo, 35 53100 Siena, (Italy). Electronic address: carla.scali@outlook.com.
Neurobiol Dis ; 86: 41-51, 2016 Feb.
Article in En | MEDLINE | ID: mdl-26626080
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Nuclear Proteins / Huntington Disease / Dependovirus / Corpus Striatum / Disease Models, Animal / Drug Discovery / Genetic Vectors / Nerve Tissue Proteins Type of study: Risk_factors_studies Limits: Animals Language: En Journal: Neurobiol Dis Journal subject: NEUROLOGIA Year: 2016 Document type: Article
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Nuclear Proteins / Huntington Disease / Dependovirus / Corpus Striatum / Disease Models, Animal / Drug Discovery / Genetic Vectors / Nerve Tissue Proteins Type of study: Risk_factors_studies Limits: Animals Language: En Journal: Neurobiol Dis Journal subject: NEUROLOGIA Year: 2016 Document type: Article