Glycoprotein isolated from Styrax japonica Siebold et al. Zuccarini inhibits oxidative and pro-inflammatory responses in HCT116 colonic epithelial cells and dextran sulfate sodium-treated ICR mice.

Lee, Sei-Jung; Lee, Jin; Song, Sooyeon; Lim, Kye-Taek

Glycoprotein isolated from Styrax japonica Siebold et al. Zuccarini inhibits oxidative and pro-inflammatory responses in HCT116 colonic epithelial cells and dextran sulfate sodium-treated ICR mice.

Lee, Sei-Jung; Lee, Jin; Song, Sooyeon; Lim, Kye-Taek.

Affiliation

Lee SJ; Department of Veterinary Physiology, College of Veterinary Medicine, Research Institute for Veterinary Science, and BK21 PLUS Creative Veterinary Research Center, Seoul National University, Seoul 08826, South Korea.
Lee J; Department of Pathology, School of Medicine, University of California at San Diego La Jolla, CA 92093-0864, USA.
Song S; Division of Animal Science, Chonnam National University, 77 Yongbong-ro, Gwangju 61186, South Korea.
Lim KT; Division of Animal Science, Chonnam National University, 77 Yongbong-ro, Gwangju 61186, South Korea. Electronic address: ktlim@chonnam.ac.kr.

Food Chem Toxicol ; 87: 12-22, 2016 Jan.

Article in En | MEDLINE | ID: mdl-26631293

Subject(s)

Colitis/chemically induced; Dextran Sulfate/toxicity; Glycoproteins/pharmacology; Inflammation/drug therapy; Oxidative Stress/drug effects; Styrax/chemistry; Animals; Colitis/drug therapy; Cyclooxygenase 2/genetics; Cyclooxygenase 2/metabolism; Gene Expression Regulation/drug effects; Glycoproteins/chemistry; HCT116 Cells; Humans; L-Lactate Dehydrogenase/blood; L-Lactate Dehydrogenase/metabolism; Male; Mice; Mice, Inbred ICR; NF-kappa B/genetics; NF-kappa B/metabolism; Nitric Oxide/blood; Nitric Oxide/metabolism; Nitric Oxide Synthase Type II/genetics; Nitric Oxide Synthase Type II/metabolism; Reactive Oxygen Species; Thiobarbituric Acid Reactive Substances/metabolism

Key words

Colonic epithelial cells; Dextran sodium sulfate; Hydroxyl radicals; Mouse colitis; SJSZ glycoprotein

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Glycoproteins / Dextran Sulfate / Colitis / Oxidative Stress / Styrax / Inflammation Limits: Animals / Humans / Male Language: En Journal: Food Chem Toxicol Year: 2016 Document type: Article Affiliation country: South Korea Country of publication: United kingdom

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