Gout on CT of the feet: A symmetric arthropathy.
J Med Imaging Radiat Oncol
; 60(1): 54-8, 2016 Feb.
Article
in En
| MEDLINE
| ID: mdl-26631920
ABSTRACT
INTRODUCTION:
The aim of this study was to assess the distribution of bone erosions in the feet of patients with gout using CT and thereby to test the hypothesis that gout is an asymmetric arthropathy.METHODS:
CT scans of both feet were obtained from 25 patients with chronic gout. CT scans were scored for bone erosion using a semi-quantitative method based on the rheumatoid arthritis MRI scoring system (RAMRIS). CT bone erosion was assessed at 22 bones in each foot (total 1,100 bones) by two independent radiologists. Symmetry was assessed by twomethods:
(i) comparing right and left foot scores for each patient; and (ii) calculating the proportion of paired joints with or without erosions.RESULTS:
Observer agreement was excellent (intra-class correlation coefficient 0.92). In the group overall, the difference in scores between the feet was not significant (Student's t-test P = 0.8). In 17 of 25 patients, the difference in erosion scores between the two feet was less than the inter-observer difference. In 24 of 25 patients, the proportion of paired joints was greater than 0.5, indicating symmetric disease.CONCLUSIONS:
Erosive disease from gout is, in fact, a symmetric process in our patient group. This finding is contrary to the established view of gout as an asymmetric arthritis and lends new insight into the behaviour of this common disease.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Foot Bones
/
Arthrography
/
Arthritis, Gouty
/
Tomography, X-Ray Computed
/
Foot Diseases
Type of study:
Diagnostic_studies
Limits:
Adult
/
Aged
/
Aged80
/
Humans
/
Middle aged
Language:
En
Journal:
J Med Imaging Radiat Oncol
Journal subject:
DIAGNOSTICO POR IMAGEM
/
NEOPLASIAS
/
RADIOLOGIA
Year:
2016
Document type:
Article
Affiliation country:
New Zealand