A Highly Selective Inhibitor of Glycine Transporter-1 Elevates the Threshold for Maximal Electroshock-Induced Tonic Seizure in Mice.

Zhao, Jianghao; Tao, Hua; Xian, Wenchuan; Cai, Yujie; Cheng, Wanwen; Yin, Mingkang; Liang, Guocong; Li, Keshen; Cui, Lili; Zhao, Bin

Zhao, Jianghao; Tao, Hua; Xian, Wenchuan; Cai, Yujie; Cheng, Wanwen; Yin, Mingkang; Liang, Guocong; Li, Keshen; Cui, Lili; Zhao, Bin.

Affiliation

Zhao J; Institute of Neurology, Affiliated Hospital of Guangdong Medical University.

Biol Pharm Bull ; 39(2): 174-80, 2016.

Article in En | MEDLINE | ID: mdl-26632210

Subject(s)

Anticonvulsants/pharmacology; Benzamides/pharmacology; Electroshock/adverse effects; Glycine Plasma Membrane Transport Proteins/antagonists & inhibitors; Piperidines/pharmacology; Seizures/prevention & control; Animals; Dose-Response Relationship, Drug; Glycine Plasma Membrane Transport Proteins/genetics; Glycine Plasma Membrane Transport Proteins/metabolism; Injections, Intravenous; Kinetics; Mice; Mice, Inbred C57BL; Molecular Structure; Pentylenetetrazole/administration & dosage; Pentylenetetrazole/toxicity; Seizures/etiology; Strychnine/toxicity

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Piperidines / Seizures / Benzamides / Electroshock / Glycine Plasma Membrane Transport Proteins / Anticonvulsants Type of study: Etiology_studies Limits: Animals Language: En Journal: Biol Pharm Bull Journal subject: BIOQUIMICA / FARMACOLOGIA Year: 2016 Document type: Article Country of publication: Japan

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google