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CYP1A1 and CYP1A2 expression levels are differentially regulated in three-dimensional spheroids of liver cancer cells compared to two-dimensional monolayer cultures.
Terashima, Jun; Goto, Shinpei; Hattori, Hiroki; Hoshi, Sawaka; Ushirokawa, Midori; Kudo, Kenzo; Habano, Wataru; Ozawa, Shogo.
Affiliation
  • Terashima J; Pharmacodynamics and Molecular Genetics, School of Pharmacy, Iwate Medical University, 2-1-1 Nishitokuda, Yahaba-CHO, Siwa-Gun, Iwate 028-3694, Japan. Electronic address: jterashi@iwate-med.ac.jp.
  • Goto S; Pharmacodynamics and Molecular Genetics, School of Pharmacy, Iwate Medical University, 2-1-1 Nishitokuda, Yahaba-CHO, Siwa-Gun, Iwate 028-3694, Japan; Department of Pharmacy, Iwate Medical University Hospital, 19-1 Uchimaru, Morioka, Iwate 020-8505, Japan.
  • Hattori H; Pharmacodynamics and Molecular Genetics, School of Pharmacy, Iwate Medical University, 2-1-1 Nishitokuda, Yahaba-CHO, Siwa-Gun, Iwate 028-3694, Japan.
  • Hoshi S; Pharmacodynamics and Molecular Genetics, School of Pharmacy, Iwate Medical University, 2-1-1 Nishitokuda, Yahaba-CHO, Siwa-Gun, Iwate 028-3694, Japan.
  • Ushirokawa M; Pharmacodynamics and Molecular Genetics, School of Pharmacy, Iwate Medical University, 2-1-1 Nishitokuda, Yahaba-CHO, Siwa-Gun, Iwate 028-3694, Japan.
  • Kudo K; Department of Pharmacy, Iwate Medical University Hospital, 19-1 Uchimaru, Morioka, Iwate 020-8505, Japan.
  • Habano W; Pharmacodynamics and Molecular Genetics, School of Pharmacy, Iwate Medical University, 2-1-1 Nishitokuda, Yahaba-CHO, Siwa-Gun, Iwate 028-3694, Japan.
  • Ozawa S; Pharmacodynamics and Molecular Genetics, School of Pharmacy, Iwate Medical University, 2-1-1 Nishitokuda, Yahaba-CHO, Siwa-Gun, Iwate 028-3694, Japan.
Drug Metab Pharmacokinet ; 30(6): 434-40, 2015 Dec.
Article in En | MEDLINE | ID: mdl-26643992

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cell Culture Techniques / Cytochrome P-450 CYP1A1 / Cytochrome P-450 CYP1A2 / Liver Neoplasms Type of study: Prognostic_studies Limits: Humans Language: En Journal: Drug Metab Pharmacokinet Journal subject: FARMACOLOGIA / METABOLISMO Year: 2015 Document type: Article Country of publication: United kingdom

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cell Culture Techniques / Cytochrome P-450 CYP1A1 / Cytochrome P-450 CYP1A2 / Liver Neoplasms Type of study: Prognostic_studies Limits: Humans Language: En Journal: Drug Metab Pharmacokinet Journal subject: FARMACOLOGIA / METABOLISMO Year: 2015 Document type: Article Country of publication: United kingdom