MicroRNA-31 initiates lung tumorigenesis and promotes mutant KRAS-driven lung cancer.

Edmonds, Mick D; Boyd, Kelli L; Moyo, Tamara; Mitra, Ramkrishna; Duszynski, Robert; Arrate, Maria Pia; Chen, Xi; Zhao, Zhongming; Blackwell, Timothy S; Andl, Thomas; Eischen, Christine M

Edmonds, Mick D; Boyd, Kelli L; Moyo, Tamara; Mitra, Ramkrishna; Duszynski, Robert; Arrate, Maria Pia; Chen, Xi; Zhao, Zhongming; Blackwell, Timothy S; Andl, Thomas; Eischen, Christine M.

J Clin Invest ; 126(1): 349-64, 2016 Jan.

Article in En | MEDLINE | ID: mdl-26657862

Subject(s)

Adenocarcinoma/etiology; Lung Neoplasms/etiology; MicroRNAs/physiology; Mutation; Proto-Oncogene Proteins p21(ras)/genetics; Adenocarcinoma/genetics; Adenocarcinoma/mortality; Adenocarcinoma of Lung; Animals; Cell Line, Tumor; Female; Humans; Lung Neoplasms/genetics; Lung Neoplasms/mortality; MAP Kinase Signaling System; Male; Mice; NIH 3T3 Cells; ras Proteins/physiology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Adenocarcinoma / Proto-Oncogene Proteins p21(ras) / MicroRNAs / Lung Neoplasms / Mutation Limits: Animals / Female / Humans / Male Language: En Journal: J Clin Invest Year: 2016 Document type: Article Country of publication: United States

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