Attenuation in rats of impairments of memory by scopolamine, a muscarinic receptor antagonist, by mecamylamine, a nicotinic receptor antagonist.

Newman, L A; Gold, P E

Newman, L A; Gold, P E.

Affiliation

Newman LA; Department of Biology, Syracuse University, 114 Life Sciences Complex, Syracuse, NY, 13244, USA.
Gold PE; Department of Biology, Syracuse University, 114 Life Sciences Complex, Syracuse, NY, 13244, USA. pegold@syr.edu.

Psychopharmacology (Berl) ; 233(5): 925-32, 2016 Mar.

Article in En | MEDLINE | ID: mdl-26660295

Subject(s)

Mecamylamine/therapeutic use; Memory Disorders/drug therapy; Memory Disorders/prevention & control; Muscarinic Antagonists; Nicotinic Antagonists/therapeutic use; Scopolamine; Acetylcholine/metabolism; Animals; Cognition/drug effects; Dose-Response Relationship, Drug; Hippocampus/drug effects; Hippocampus/metabolism; Male; Memory, Short-Term/drug effects; Nicotinic Agonists/pharmacology; Rats; Rats, Sprague-Dawley; Spatial Memory/drug effects

Key words

Aging; Alzheimer; Autoreceptor; Cholinergic; Cholinesterase inhibitor; Hippocampus; In vivo microdialysis; Muscarinic; Nicotinic; Spatial working memory

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Scopolamine / Nicotinic Antagonists / Muscarinic Antagonists / Mecamylamine / Memory Disorders Limits: Animals Language: En Journal: Psychopharmacology (Berl) Year: 2016 Document type: Article Affiliation country: United States Country of publication: Germany

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