Synthesis and antimicrobial evaluation of 20-deoxo-20-(3,5-dimethylpiperidin-1-yl)desmycosin (tilmicosin, EL-870) and related cyclic amino derivatives.

Debono, M; Willard, K E; Kirst, H A; Wind, J A; Crouse, G D; Tao, E V; Vicenzi, J T; Counter, F T; Ott, J L; Ose, E E

Debono, M; Willard, K E; Kirst, H A; Wind, J A; Crouse, G D; Tao, E V; Vicenzi, J T; Counter, F T; Ott, J L; Ose, E E.

Affiliation

Debono M; Lilly Research Laboratories, Lilly Corporate Center, Eli Lilly and Company, Indianapolis, IN 46285.

J Antibiot (Tokyo) ; 42(8): 1253-67, 1989 Aug.

Article in En | MEDLINE | ID: mdl-2668243

Subject(s)

Anti-Bacterial Agents; Leucomycins/chemical synthesis; Macrolides; Tylosin/analogs & derivatives; Amination; Animals; Chickens; Leucomycins/pharmacology; Leucomycins/therapeutic use; Mice; Microbial Sensitivity Tests; Molecular Structure; Mycoplasma/drug effects; Oxidation-Reduction; Pasteurella/drug effects; Pasteurella Infections/drug therapy; Streptococcal Infections/drug therapy; Streptococcus pyogenes

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Collection: 01-internacional Database: MEDLINE Main subject: Tylosin / Leucomycins / Macrolides / Anti-Bacterial Agents Limits: Animals Language: En Journal: J Antibiot (Tokyo) Year: 1989 Document type: Article Country of publication: United kingdom

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