The cholecystokinin-1 receptor antagonist devazepide increases cholesterol cholelithogenesis in mice.

Wang, Helen H; Portincasa, Piero; Wang, David Q-H

Wang, Helen H; Portincasa, Piero; Wang, David Q-H.

Affiliation

Wang HH; Department of Medicine, Liver Center and Gastroenterology Division, Beth Israel Deaconess Medical Center, Harvard Medical School and Harvard Digestive Diseases Center, Boston, MA, USA.
Portincasa P; Department of Internal Medicine, Division of Gastroenterology and Hepatology, Saint Louis University School of Medicine, St. Louis, MO, USA.
Wang DQ; Clinica Medica "A. Murri", Department of Biomedical Sciences and Human Oncology, University of Bari Medical School, Bari, Italy.

Eur J Clin Invest ; 46(2): 158-69, 2016 Feb.

Article in En | MEDLINE | ID: mdl-26683129

Subject(s)

Cholelithiasis/chemically induced; Cholesterol/metabolism; Devazepide/pharmacology; Gallbladder Emptying/drug effects; Gallbladder/drug effects; Hormone Antagonists/pharmacology; Intestines/drug effects; Receptor, Cholecystokinin A/antagonists & inhibitors; Animals; Bile Acids and Salts/metabolism; Cholelithiasis/metabolism; Gallbladder/metabolism; Intestinal Mucosa/metabolism; Male; Mice; Mice, Inbred C57BL; Receptor, Cholecystokinin A/drug effects; Receptor, Cholecystokinin A/genetics

Key words

Bile salts; biliary secretion; cholesterol crystallization; gallbladder motility; gallstones; mucin

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cholelithiasis / Cholesterol / Gallbladder Emptying / Devazepide / Receptor, Cholecystokinin A / Gallbladder / Hormone Antagonists / Intestines Limits: Animals Language: En Journal: Eur J Clin Invest Year: 2016 Document type: Article Affiliation country: United States Country of publication: United kingdom

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google