Hoxb6 can interfere with somitogenesis in the posterior embryo through a mechanism independent of its rib-promoting activity.

Casaca, Ana; Nóvoa, Ana; Mallo, Moisés

Casaca, Ana; Nóvoa, Ana; Mallo, Moisés.

Affiliation

Casaca A; Instituto Gulbenkian de Ciência, Oeiras 2780-156, Portugal.
Nóvoa A; Instituto Gulbenkian de Ciência, Oeiras 2780-156, Portugal.
Mallo M; Instituto Gulbenkian de Ciência, Oeiras 2780-156, Portugal mallo@igc.gulbenkian.pt.

Development ; 143(3): 437-48, 2016 Feb 01.

Article in En | MEDLINE | ID: mdl-26718008

Subject(s)

Embryo, Mammalian/metabolism; Homeodomain Proteins/metabolism; Organogenesis/genetics; Ribs/embryology; Somites/embryology; Amino Acid Sequence; Animals; Base Sequence; Calcium-Binding Proteins; DNA/metabolism; Gene Expression Regulation, Developmental; Homeodomain Proteins/chemistry; Homeodomain Proteins/genetics; Intercellular Signaling Peptides and Proteins/metabolism; Mice, Transgenic; MicroRNAs/genetics; MicroRNAs/metabolism; Molecular Sequence Data; Mutant Proteins/metabolism; Phenotype; Protein Binding/genetics; Ribs/metabolism

Key words

Axial skeleton; Gene regulation; Hox genes; Mouse; Vertebrate patterning

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ribs / Homeodomain Proteins / Somites / Organogenesis / Embryo, Mammalian Limits: Animals Language: En Journal: Development Journal subject: BIOLOGIA / EMBRIOLOGIA Year: 2016 Document type: Article Affiliation country: Portugal Country of publication: United kingdom

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