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Lanatoside C suppressed colorectal cancer cell growth by inducing mitochondrial dysfunction and increased radiation sensitivity by impairing DNA damage repair.
Kang, Mi Ae; Kim, Mi-Sook; Kim, Wonwoo; Um, Jee-Hyun; Shin, Young-Joo; Song, Jie-Young; Jeong, Jae-Hoon.
Affiliation
  • Kang MA; Research Center for Radiotherapy, Korea Institute of Radiological and Medical Sciences, Seoul, Korea.
  • Kim MS; Research Center for Radiotherapy, Korea Institute of Radiological and Medical Sciences, Seoul, Korea.
  • Kim W; Department of Radiation Oncology, Korea Institute of Radiological and Medical Sciences, Seoul, Korea.
  • Um JH; Research Center for Radiotherapy, Korea Institute of Radiological and Medical Sciences, Seoul, Korea.
  • Shin YJ; Korea Mouse Metabolic Phenotyping Center, Lee Gil Ya Cancer and Diabetes Institute, Gachon University, Incheon, Korea.
  • Song JY; Department of Radiation Oncology, Inje University Sanggye Paik Hospital, Seoul, Korea.
  • Jeong JH; Division of Radiation Cancer Research, Korea Institute of Radiological and Medical Sciences, Seoul, Korea.
Oncotarget ; 7(5): 6074-87, 2016 Feb 02.
Article in En | MEDLINE | ID: mdl-26756216
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Colorectal Neoplasms / DNA Repair / Lanatosides / Mitochondria Type of study: Clinical_trials / Diagnostic_studies Limits: Animals / Humans Language: En Journal: Oncotarget Year: 2016 Document type: Article Country of publication: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Colorectal Neoplasms / DNA Repair / Lanatosides / Mitochondria Type of study: Clinical_trials / Diagnostic_studies Limits: Animals / Humans Language: En Journal: Oncotarget Year: 2016 Document type: Article Country of publication: United States