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A randomized, double-blind, placebo-controlled phase II study to assess the efficacy and safety of mapatumumab with sorafenib in patients with advanced hepatocellular carcinoma.
Ciuleanu, T; Bazin, I; Lungulescu, D; Miron, L; Bondarenko, I; Deptala, A; Rodriguez-Torres, M; Giantonio, B; Fox, N L; Wissel, P; Egger, J; Ding, M; Kalyani, R N; Humphreys, R; Gribbin, M; Sun, W.
Affiliation
  • Ciuleanu T; Department of Medical Oncology, Prof. Dr Ion Chiricuta Institute of Oncology and UMF Iuliu Hatieganu, Cluj Napoca, Romania tudor@iocn.ro.
  • Bazin I; Federal State Budgetary Institution, Russian Oncology Research Center n.a. N.N. Blokhin under the Russian Academy of Medical Sciences, Moscow, Russia.
  • Lungulescu D; SC Oncolab SRL, Dolj County.
  • Miron L; Iasi Regional Institute for Oncology, Iasi County, Romania.
  • Bondarenko I; Department of Oncology and Medical Radiology, Dnipropetrovsk Medical Academy, City Multispeciality Clinical Hospital # 4, Dnipropetrovsk, Ukraine.
  • Deptala A; Department of Oncology and Hematology, CSK MSW, Warsaw Department of Cancer Prevention, WNOZ WUM, Warsaw, Poland.
  • Rodriguez-Torres M; Fundacion de Investigacion, San Juan, Puerto Rico.
  • Giantonio B; Department of Hematology-Oncology, Abramson Cancer Center of the University of Pennsylvania, Philadelphia.
  • Fox NL; Clinical Development, Human Genome Sciences, Inc., Rockville.
  • Wissel P; Clinical Development, GlaxoSmithKline, Upper Providence, USA.
  • Egger J; Clinical Development, GlaxoSmithKline, Stockley Park, UK.
  • Ding M; Statistics, GlaxoSmithKline, Upper Providence.
  • Kalyani RN; Clinical Development, Human Genome Sciences, Inc., Rockville.
  • Humphreys R; Oncology Research.
  • Gribbin M; Statistics, Human Genome Sciences, Inc., Rockville, USA.
  • Sun W; Department of Hematology-Oncology, Abramson Cancer Center of the University of Pennsylvania, Philadelphia.
Ann Oncol ; 27(4): 680-7, 2016 Apr.
Article in En | MEDLINE | ID: mdl-26802147
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Phenylurea Compounds / Niacinamide / Carcinoma, Hepatocellular / Liver Neoplasms / Antibodies, Monoclonal Type of study: Clinical_trials / Prognostic_studies Limits: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Language: En Journal: Ann Oncol Journal subject: NEOPLASIAS Year: 2016 Document type: Article Affiliation country: Romania
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Phenylurea Compounds / Niacinamide / Carcinoma, Hepatocellular / Liver Neoplasms / Antibodies, Monoclonal Type of study: Clinical_trials / Prognostic_studies Limits: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Language: En Journal: Ann Oncol Journal subject: NEOPLASIAS Year: 2016 Document type: Article Affiliation country: Romania