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Up-regulation of genes involved in the insulin signalling pathway (IGF1, PTEN and IGFBP1) in the endometrium may link polycystic ovarian syndrome and endometrial cancer.
Shafiee, Mohamad Nasir; Seedhouse, Claire; Mongan, Nigel; Chapman, Caroline; Deen, Suha; Abu, Jafaru; Atiomo, William.
Affiliation
  • Shafiee MN; Division of Obstetrics and Gynaecology and Child Health, School of Medicine, Faculty of Medicine and Health Sciences, Queen's Medical Centre, Nottingham University Hospital, Derby Road, Nottingham, NG7 2UH, UK; Department of Obstetrics and Gynaecology, Universiti Kebangsaan Malaysia, Faculty of Medi
  • Seedhouse C; Department of Haematology, Clinical Sciences Building, University of Nottingham, Hucknall Road, Nottingham, NG5 1PB, UK.
  • Mongan N; School of Veterinary Medicine and Science, University of Nottingham, LE12 5RD, UK.
  • Chapman C; Division of Medical Sciences and Graduate Entry Medicine, Faculty of Medicine and Health Sciences, University of Nottingham, NG5 1PB, UK.
  • Deen S; Department of Pathology, Queen's Medical Centre, Nottingham University Hospital, Nottingham, NG7 2UH, UK.
  • Abu J; Department of Obstetrics and Gynaecology, City Hospital, Nottingham University Hospital, Nottingham, NG5 1PB, UK.
  • Atiomo W; Division of Obstetrics and Gynaecology and Child Health, School of Medicine, Faculty of Medicine and Health Sciences, Queen's Medical Centre, Nottingham University Hospital, Derby Road, Nottingham, NG7 2UH, UK.
Mol Cell Endocrinol ; 424: 94-101, 2016 Mar 15.
Article in En | MEDLINE | ID: mdl-26802879
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Polycystic Ovary Syndrome / Insulin-Like Growth Factor I / Up-Regulation / Endometrial Neoplasms / Intracellular Signaling Peptides and Proteins / PTEN Phosphohydrolase Type of study: Observational_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Aged / Female / Humans / Middle aged Language: En Journal: Mol Cell Endocrinol Year: 2016 Document type: Article
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Polycystic Ovary Syndrome / Insulin-Like Growth Factor I / Up-Regulation / Endometrial Neoplasms / Intracellular Signaling Peptides and Proteins / PTEN Phosphohydrolase Type of study: Observational_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Aged / Female / Humans / Middle aged Language: En Journal: Mol Cell Endocrinol Year: 2016 Document type: Article