A new ratiometric fluorescent probe for rapid, sensitive and selective detection of endogenous hydrogen sulfide in mitochondria.
Chem Commun (Camb)
; 52(15): 3131-4, 2016 Feb 21.
Article
in En
| MEDLINE
| ID: mdl-26806758
ABSTRACT
We have developed a new ratiometric fluorescent probe composed of a coumarin-merocyanine dyad based on the FRET mechanism. The probe showed clear dual-emission signal changes in blue and red spectral windows upon addition of H2S in a dose dependent manner under a single wavelength excitation. The probe targeted mitochondria with high selectivity and sensitivity toward H2S.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Fluorescent Dyes
/
Hydrogen Sulfide
/
Mitochondria
Type of study:
Diagnostic_studies
Language:
En
Journal:
Chem Commun (Camb)
Journal subject:
QUIMICA
Year:
2016
Document type:
Article
Publication country:
ENGLAND
/
ESCOCIA
/
GB
/
GREAT BRITAIN
/
INGLATERRA
/
REINO UNIDO
/
SCOTLAND
/
UK
/
UNITED KINGDOM