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A direct interaction between NQO1 and a chemotherapeutic dimeric naphthoquinone.
Pidugu, Lakshmi Swarna Mukhi; Mbimba, J C Emmanuel; Ahmad, Muqeet; Pozharski, Edwin; Sausville, Edward A; Emadi, Ashkan; Toth, Eric A.
Affiliation
  • Pidugu LS; Department of Biochemistry and Molecular Biology, University of Maryland School of Medicine, Baltimore, MD, 21201, USA. Pidugu@ibbr.umd.edu.
  • Mbimba JC; Marlene and Stewart Greenebaum Cancer Center, University of Maryland School of Medicine, Baltimore, MD, 21201, USA. Pidugu@ibbr.umd.edu.
  • Ahmad M; Institute for Bioscience and Biotechnology Research, and Center for Biomolecular Therapeutics, 9600 Gudelsky Drive, Rockville, MD, 20850, USA. Pidugu@ibbr.umd.edu.
  • Pozharski E; Institute for Bioscience and Biotechnology Research, and Center for Biomolecular Therapeutics, 9600 Gudelsky Drive, Rockville, MD, 20850, USA. J_mbimba@yahoo.com.
  • Sausville EA; Institute for Bioscience and Biotechnology Research, and Center for Biomolecular Therapeutics, 9600 Gudelsky Drive, Rockville, MD, 20850, USA. ahmad.muqeet@gmail.com.
  • Emadi A; Department of Biochemistry and Molecular Biology, University of Maryland School of Medicine, Baltimore, MD, 21201, USA. epozharskiy@som.umaryland.edu.
  • Toth EA; Marlene and Stewart Greenebaum Cancer Center, University of Maryland School of Medicine, Baltimore, MD, 21201, USA. epozharskiy@som.umaryland.edu.
BMC Struct Biol ; 16: 1, 2016 Jan 28.
Article in En | MEDLINE | ID: mdl-26822308
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Naphthoquinones / NAD(P)H Dehydrogenase (Quinone) / Antineoplastic Agents Type of study: Prognostic_studies Language: En Journal: BMC Struct Biol Journal subject: BIOLOGIA Year: 2016 Document type: Article Affiliation country: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Naphthoquinones / NAD(P)H Dehydrogenase (Quinone) / Antineoplastic Agents Type of study: Prognostic_studies Language: En Journal: BMC Struct Biol Journal subject: BIOLOGIA Year: 2016 Document type: Article Affiliation country: United States