The Evolution of Pressurized Metered-Dose Inhalers from Early to Modern Devices.

Roche, Nicolas; Dekhuijzen, P N Richard

Roche, Nicolas; Dekhuijzen, P N Richard.

Affiliation

Roche N; 1 University Paris Descartes , Paris, France .
Dekhuijzen PN; 2 Radboud University Medical Centre , Nijmegen, The Netherlands .

J Aerosol Med Pulm Drug Deliv ; 29(4): 311-27, 2016 08.

Article in En | MEDLINE | ID: mdl-26824873

Subject(s)

Anti-Asthmatic Agents/administration & dosage; Asthma/drug therapy; Drug Delivery Systems/instrumentation; Lung/drug effects; Pulmonary Disease, Chronic Obstructive/drug therapy; Administration, Inhalation; Aerosols; Anti-Asthmatic Agents/chemistry; Anti-Asthmatic Agents/pharmacokinetics; Asthma/physiopathology; Diffusion of Innovation; Drug Delivery Systems/history; Drug Delivery Systems/trends; Equipment Design; History, 19th Century; History, 20th Century; History, 21st Century; Humans; Lung/metabolism; Lung/physiopathology; Medication Adherence; Metered Dose Inhalers/history; Metered Dose Inhalers/trends; Particle Size; Patient Education as Topic; Patient Preference; Pressure; Pulmonary Disease, Chronic Obstructive/physiopathology; Tissue Distribution

Key words

aerosol distribution; inhaled therapy; metered dose inhaler; modeling

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Asthma / Drug Delivery Systems / Anti-Asthmatic Agents / Pulmonary Disease, Chronic Obstructive / Lung Type of study: Prognostic_studies / Sysrev_observational_studies Limits: Humans Language: En Journal: J Aerosol Med Pulm Drug Deliv Journal subject: TERAPIA POR MEDICAMENTOS Year: 2016 Document type: Article Affiliation country: France Country of publication: United States

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