Modern Methods for Interrogating the Human Connectome.
J Int Neuropsychol Soc
; 22(2): 105-19, 2016 Feb.
Article
in En
| MEDLINE
| ID: mdl-26888611
ABSTRACT
OBJECTIVES:
Connectionist theories of brain function took hold with the seminal contributions of Norman Geschwind a half century ago. Modern neuroimaging techniques have expanded the scientific interest in the study of brain connectivity to include the intact as well as disordered brain.METHODS:
In this review, we describe the most common techniques used to measure functional and structural connectivity, including resting state functional MRI, diffusion MRI, and electroencephalography and magnetoencephalography coherence. We also review the most common analytical approaches used for examining brain interconnectivity associated with these various imaging methods.RESULTS:
This review presents a critical analysis of the assumptions, as well as methodological limitations, of each imaging and analysis approach.CONCLUSIONS:
The overall goal of this review is to provide the reader with an introduction to evaluating the scientific methods underlying investigations that probe the human connectome.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Brain
/
Electrophysiology
/
Neuroimaging
/
Connectome
Limits:
Humans
Language:
En
Journal:
J Int Neuropsychol Soc
Journal subject:
NEUROLOGIA
/
PSICOLOGIA
Year:
2016
Document type:
Article