Anesthetic propofol normalized the increased release of glutamate and Î³-amino butyric acid in hippocampus after paradoxical sleep deprivation in rats.

Xie, Fang; Li, Xueyang; Bao, Mengmeng; Shi, Rong; Yue, Yun; Guan, Yun; Wang, Yun

Xie, Fang; Li, Xueyang; Bao, Mengmeng; Shi, Rong; Yue, Yun; Guan, Yun; Wang, Yun.

Affiliation

Xie F; 1 Department of Anesthesiology, Beijing Chaoyang Hospital, Capital Medical University , Beijing 100020, China.

Neurol Res ; 37(12): 1102-7, 2015.

Article in En | MEDLINE | ID: mdl-26923580

Subject(s)

Glutamic Acid/metabolism; Hippocampus/drug effects; Hypnotics and Sedatives/therapeutic use; Propofol/therapeutic use; Sleep Deprivation/drug therapy; gamma-Aminobutyric Acid/metabolism; Animals; Hippocampus/metabolism; Hypnotics and Sedatives/pharmacology; Male; Microdialysis; Propofol/pharmacology; Rats; Rats, Sprague-Dawley; Sleep Deprivation/pathology; Time Factors

Key words

Anesthesia; Hippocampus; Neurochemistry; Sleep deprivation

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sleep Deprivation / Propofol / Glutamic Acid / Gamma-Aminobutyric Acid / Hippocampus / Hypnotics and Sedatives Limits: Animals Language: En Journal: Neurol Res Year: 2015 Document type: Article Affiliation country: China Country of publication: United kingdom

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