Blood gene expression profiling of an early acetaminophen response.

Bushel, P R; Fannin, R D; Gerrish, K; Watkins, P B; Paules, R S

Bushel, P R; Fannin, R D; Gerrish, K; Watkins, P B; Paules, R S.

Affiliation

Bushel PR; Microarray and Genome Informatics Group, National Institute of Environmental Health Sciences, Research Triangle Park, NC, USA.
Fannin RD; Biostatistics Branch, National Institute of Environmental Health Sciences, Research Triangle Park, NC, USA.
Gerrish K; Molecular Genomics Core, National Institute of Environmental Health Sciences, Research Triangle Park, NC, USA.
Watkins PB; Laboratory of Toxicology and Pharmacology, National Institute of Environmental Health Sciences, Research Triangle Park, NC, USA.
Paules RS; Molecular Genomics Core, National Institute of Environmental Health Sciences, Research Triangle Park, NC, USA.

Pharmacogenomics J ; 17(3): 230-236, 2017 06.

Article in En | MEDLINE | ID: mdl-26927286

Subject(s)

Acetaminophen/adverse effects; Analgesics, Non-Narcotic/adverse effects; Drug Overdose/genetics; Gene Expression Profiling/methods; Pharmacogenomic Testing/methods; Pharmacogenomic Variants; RNA/genetics; Transcriptome; Acetaminophen/administration & dosage; Administration, Oral; Adolescent; Adult; Alanine Transaminase/blood; Analgesics, Non-Narcotic/administration & dosage; Biomarkers/blood; Drug Administration Schedule; Drug Overdose/blood; Female; Gene Regulatory Networks; Healthy Volunteers; Humans; Male; Middle Aged; Models, Genetic; Oligonucleotide Array Sequence Analysis; Pharmacogenetics; RNA/blood; Single-Blind Method; Time Factors; Young Adult

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: RNA / Analgesics, Non-Narcotic / Gene Expression Profiling / Transcriptome / Drug Overdose / Pharmacogenomic Testing / Pharmacogenomic Variants / Acetaminophen Type of study: Clinical_trials / Prognostic_studies Limits: Adolescent / Adult / Female / Humans / Male / Middle aged Language: En Journal: Pharmacogenomics J Journal subject: BIOLOGIA MOLECULAR / FARMACOLOGIA Year: 2017 Document type: Article Affiliation country: United States

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