Interaction of an anti-cancer photosensitizer with a genomic DNA: From base pair specificity and thermodynamic landscape to tuning the rate of detergent-sequestered dissociation.

Paul, Bijan K; Ghosh, Narayani; Mukherjee, Saptarshi

Paul, Bijan K; Ghosh, Narayani; Mukherjee, Saptarshi.

Affiliation

Paul BK; Department of Chemistry, Indian Institute of Science Education and Research Bhopal, Bhopal Bypass Road, Bhauri, Bhopal 462066, Madhya Pradesh, India. Electronic address: bpaul@iiserb.ac.in.
Ghosh N; Department of Chemistry, Indian Institute of Science Education and Research Bhopal, Bhopal Bypass Road, Bhauri, Bhopal 462066, Madhya Pradesh, India.
Mukherjee S; Department of Chemistry, Indian Institute of Science Education and Research Bhopal, Bhopal Bypass Road, Bhauri, Bhopal 462066, Madhya Pradesh, India. Electronic address: saptarshi@iiserb.ac.in.

J Colloid Interface Sci ; 470: 211-220, 2016 May 15.

Article in En | MEDLINE | ID: mdl-26945117

Subject(s)

Antineoplastic Agents/chemistry; Base Pairing; Carbolines/chemistry; DNA/chemistry; Detergents/chemistry; Photosensitizing Agents/chemistry; Thermodynamics; Animals; Cattle; DNA/genetics; Fishes; Male; Spermatozoa/chemistry

Key words

Detergent-sequestered drug dissociation; Intercalation; Interplay of various binding forces; NHM-hsDNA interaction; Thermodynamics; Tuning the rate of dissociation

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Thermodynamics / DNA / Carbolines / Photosensitizing Agents / Base Pairing / Detergents / Antineoplastic Agents Limits: Animals Language: En Journal: J Colloid Interface Sci Year: 2016 Document type: Article Country of publication: United States

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