Fab(nimotuzumab)-HYNIC-99mTc: Antibody Fragmentation for Molecular Imaging Agents.

Calzada, Victoria; García, María Fernanda; Alonso-Martínez, Luis Michel; Camachoc, Ximena; Goicochea, Enzo; Fernández, Marcelo; Castillo, Abmel Xiques; Díaz-Miqueli, Arlhee; Iznaga-Escobar, Normando; Montaña, René Leyva; Alonso, Omar; Gambini, Juan Pablo; Cabral, Pablo

Calzada, Victoria; García, María Fernanda; Alonso-Martínez, Luis Michel; Camachoc, Ximena; Goicochea, Enzo; Fernández, Marcelo; Castillo, Abmel Xiques; Díaz-Miqueli, Arlhee; Iznaga-Escobar, Normando; Montaña, René Leyva; Alonso, Omar; Gambini, Juan Pablo; Cabral, Pablo.

Affiliation

Calzada V; Departamento de Radiofarmacia, Centro de Investigaciones Nucleares, Facultad de Ciencias, Universidad de la República, Uruguay. vcalzada@cin.edu.uy.

Anticancer Agents Med Chem ; 16(9): 1184-9, 2016.

Article in En | MEDLINE | ID: mdl-26961312

Subject(s)

Adenocarcinoma/diagnostic imaging; Antibodies, Monoclonal, Humanized/analysis; ErbB Receptors/analysis; Hydrazines/analysis; Molecular Imaging/methods; Nicotinic Acids/analysis; Technetium/analysis; Animals; Antibodies, Monoclonal, Humanized/metabolism; Antibodies, Monoclonal, Humanized/pharmacokinetics; ErbB Receptors/metabolism; Humans; Hydrazines/metabolism; Hydrazines/pharmacokinetics; Mice; Nicotinic Acids/metabolism; Nicotinic Acids/pharmacokinetics; Papain/metabolism; Radionuclide Imaging/methods; Technetium/metabolism; Technetium/pharmacokinetics; Tissue Distribution

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Collection: 01-internacional Database: MEDLINE Main subject: Adenocarcinoma / Technetium / Molecular Imaging / Antibodies, Monoclonal, Humanized / ErbB Receptors / Hydrazines / Nicotinic Acids Limits: Animals / Humans Language: En Journal: Anticancer Agents Med Chem Journal subject: ANTINEOPLASICOS / QUIMICA Year: 2016 Document type: Article Affiliation country: Uruguay Country of publication: Netherlands

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