Single-step synthesis of heparin-doped polypyrrole nanoparticles for delivery of angiogenic factor.

Xiong, Gordon M; Yap, Yi Zhen; Choong, Cleo

Xiong, Gordon M; Yap, Yi Zhen; Choong, Cleo.

Affiliation

Xiong GM; School of Materials Science & Engineering, Nanyang Technological University, 50 Nanyang Avenue, 639798 Singapore.
Yap YZ; School of Materials Science & Engineering, Nanyang Technological University, 50 Nanyang Avenue, 639798 Singapore.
Choong C; School of Materials Science & Engineering, Nanyang Technological University, 50 Nanyang Avenue, 639798 Singapore.

Nanomedicine (Lond) ; 11(7): 749-65, 2016 Apr.

Article in En | MEDLINE | ID: mdl-26980324

Subject(s)

Angiogenesis Inducing Agents/administration & dosage; Drug Carriers/chemistry; Heparin/chemistry; Nanoparticles/chemistry; Polymers/chemistry; Pyrroles/chemistry; Vascular Endothelial Growth Factor A/administration & dosage; Angiogenesis Inducing Agents/pharmacology; Biocompatible Materials/chemical synthesis; Biocompatible Materials/chemistry; Cell Movement/drug effects; Drug Carriers/chemical synthesis; Heparin/chemical synthesis; Human Umbilical Vein Endothelial Cells; Humans; Materials Testing; Nanoparticles/ultrastructure; Nanotechnology; Neovascularization, Physiologic/drug effects; Polymerization; Polymers/chemical synthesis; Pyrroles/chemical synthesis; Vascular Endothelial Growth Factor A/pharmacology

Key words

VEGF delivery; angiogenesis; dispersion polymerization; heparin; nanoparticles; one-pot synthesis; polypyrrole; protein stability

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Polymers / Pyrroles / Drug Carriers / Heparin / Vascular Endothelial Growth Factor A / Angiogenesis Inducing Agents / Nanoparticles Limits: Humans Language: En Journal: Nanomedicine (Lond) Year: 2016 Document type: Article Country of publication: United kingdom

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