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Identification of IL-23p19 as an endothelial proinflammatory peptide that promotes gp130-STAT3 signaling.
Espígol-Frigolé, Georgina; Planas-Rigol, Ester; Ohnuki, Hidetaka; Salvucci, Ombretta; Kwak, Hyeongil; Ravichandran, Sarangan; Luke, Brian; Cid, Maria C; Tosato, Giovanna.
Affiliation
  • Espígol-Frigolé G; Laboratory of Cellular Oncology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA. Department of Systemic Autoimmune Diseases, Clinical Institute of Medicine and Dermatology, Hospital Clinic, University of Barcelona, IDIBAPS-CRB CELLEX, Ba
  • Planas-Rigol E; Laboratory of Cellular Oncology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA. Department of Systemic Autoimmune Diseases, Clinical Institute of Medicine and Dermatology, Hospital Clinic, University of Barcelona, IDIBAPS-CRB CELLEX, Ba
  • Ohnuki H; Laboratory of Cellular Oncology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.
  • Salvucci O; Laboratory of Cellular Oncology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.
  • Kwak H; Laboratory of Cellular Oncology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.
  • Ravichandran S; Advanced Biomedical Computing Center, Leidos Biomedical Research Inc., Frederick National Laboratory for Cancer Research, Frederick, MD 21702, USA.
  • Luke B; Advanced Biomedical Computing Center, Leidos Biomedical Research Inc., Frederick National Laboratory for Cancer Research, Frederick, MD 21702, USA.
  • Cid MC; Department of Systemic Autoimmune Diseases, Clinical Institute of Medicine and Dermatology, Hospital Clinic, University of Barcelona, IDIBAPS-CRB CELLEX, Barcelona 08036, Spain.
  • Tosato G; Laboratory of Cellular Oncology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA. georginaespigol@gmail.com tosatog@mail.nih.gov.
Sci Signal ; 9(419): ra28, 2016 Mar 15.
Article in En | MEDLINE | ID: mdl-26980441
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Signal Transduction / Inflammation Mediators / STAT3 Transcription Factor / Cytokine Receptor gp130 / Interleukin-23 Subunit p19 / Human Umbilical Vein Endothelial Cells Type of study: Diagnostic_studies / Prognostic_studies Limits: Humans Language: En Journal: Sci Signal Journal subject: CIENCIA / FISIOLOGIA Year: 2016 Document type: Article Affiliation country: Bosnia and Herzegovina Country of publication: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Signal Transduction / Inflammation Mediators / STAT3 Transcription Factor / Cytokine Receptor gp130 / Interleukin-23 Subunit p19 / Human Umbilical Vein Endothelial Cells Type of study: Diagnostic_studies / Prognostic_studies Limits: Humans Language: En Journal: Sci Signal Journal subject: CIENCIA / FISIOLOGIA Year: 2016 Document type: Article Affiliation country: Bosnia and Herzegovina Country of publication: United States