Establishment of an effective TLC bioautographic method for the detection of Mycobacterium tuberculosis H37Ra phosphoglucose isomerase inhibition by phosphoenolpyruvate.

Paradowska, Katarzyna; Polak, Beata; Chomicki, Adam; Ginalska, Grazyna

Paradowska, Katarzyna; Polak, Beata; Chomicki, Adam; Ginalska, Grazyna.

Affiliation

Paradowska K; a Chair and Department of Biochemistry and Biotechnology, Medical University of Lublin , Lublin , Poland and.
Polak B; b Department of Physical Chemistry , Medical University of Lublin , Lublin , Poland.
Chomicki A; b Department of Physical Chemistry , Medical University of Lublin , Lublin , Poland.
Ginalska G; a Chair and Department of Biochemistry and Biotechnology, Medical University of Lublin , Lublin , Poland and.

J Enzyme Inhib Med Chem ; 31(6): 1712-7, 2016 Dec.

Article in En | MEDLINE | ID: mdl-26986942

Subject(s)

Chromatography, Thin Layer/methods; Enzyme Inhibitors/pharmacology; Glucose-6-Phosphate Isomerase/antagonists & inhibitors; Mycobacterium tuberculosis/enzymology; Phosphoenolpyruvate/pharmacology

Key words

Antimycobacterial activity; autography; glycolysis; mycobacterial cell wall; potential drug target

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Phosphoenolpyruvate / Chromatography, Thin Layer / Enzyme Inhibitors / Glucose-6-Phosphate Isomerase / Mycobacterium tuberculosis Type of study: Diagnostic_studies Language: En Journal: J Enzyme Inhib Med Chem Journal subject: BIOQUIMICA / QUIMICA Year: 2016 Document type: Article Country of publication: United kingdom

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