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Dose- and Formulation-Dependent Non-Linear Pharmacokinetic Model of Paritaprevir, a Protease Inhibitor for the Treatment of Hepatitis C Virus Infection: Combined Analysis from 12 Phase I Studies.
Polepally, Akshanth R; Mensing, Sven; Khatri, Amit; Beck, Denise; Liu, Wei; Awni, Walid M; Menon, Rajeev M; Dutta, Sandeep.
Affiliation
  • Polepally AR; AbbVie, Inc., Clinical Pharmacokinetics and Pharmacodynamics, 1 North Waukegan Road, R4PK, AP31-3, North Chicago, IL, 60064, USA. akshanth.r.polepally@abbvie.com.
  • Mensing S; AbbVie, Inc., Ludwigshafen, Germany.
  • Khatri A; AbbVie, Inc., Clinical Pharmacokinetics and Pharmacodynamics, 1 North Waukegan Road, R4PK, AP31-3, North Chicago, IL, 60064, USA.
  • Beck D; AbbVie, Inc., Ludwigshafen, Germany.
  • Liu W; AbbVie, Inc., Clinical Pharmacokinetics and Pharmacodynamics, 1 North Waukegan Road, R4PK, AP31-3, North Chicago, IL, 60064, USA.
  • Awni WM; AbbVie, Inc., Clinical Pharmacokinetics and Pharmacodynamics, 1 North Waukegan Road, R4PK, AP31-3, North Chicago, IL, 60064, USA.
  • Menon RM; AbbVie, Inc., Clinical Pharmacokinetics and Pharmacodynamics, 1 North Waukegan Road, R4PK, AP31-3, North Chicago, IL, 60064, USA.
  • Dutta S; AbbVie, Inc., Clinical Pharmacokinetics and Pharmacodynamics, 1 North Waukegan Road, R4PK, AP31-3, North Chicago, IL, 60064, USA.
Clin Pharmacokinet ; 55(9): 1091-101, 2016 09.
Article in En | MEDLINE | ID: mdl-27000758
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Antiviral Agents / Protease Inhibitors / Hepatitis C / Ritonavir / Macrocyclic Compounds / Drug Compounding Type of study: Prognostic_studies Limits: Adolescent / Adult / Female / Humans / Male / Middle aged Language: En Journal: Clin Pharmacokinet Year: 2016 Document type: Article Affiliation country: United States Country of publication: Switzerland
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Antiviral Agents / Protease Inhibitors / Hepatitis C / Ritonavir / Macrocyclic Compounds / Drug Compounding Type of study: Prognostic_studies Limits: Adolescent / Adult / Female / Humans / Male / Middle aged Language: En Journal: Clin Pharmacokinet Year: 2016 Document type: Article Affiliation country: United States Country of publication: Switzerland