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Structure-Activity Relationships of a Diverse Class of Halogenated Phenazines That Targets Persistent, Antibiotic-Tolerant Bacterial Biofilms and Mycobacterium tuberculosis.
Garrison, Aaron T; Abouelhassan, Yasmeen; Norwood, Verrill M; Kallifidas, Dimitris; Bai, Fang; Nguyen, Minh Thu; Rolfe, Melanie; Burch, Gena M; Jin, Shouguang; Luesch, Hendrik; Huigens, Robert W.
Affiliation
  • Garrison AT; Department of Medicinal Chemistry, College of Pharmacy, ‡Department of Molecular Genetics & Microbiology, College of Medicine, and ⊥Center for Natural Products, Drug Discovery and Development (CNPD3), University of Florida , Gainesville, Florida 32610.
  • Abouelhassan Y; Department of Medicinal Chemistry, College of Pharmacy, ‡Department of Molecular Genetics & Microbiology, College of Medicine, and ⊥Center for Natural Products, Drug Discovery and Development (CNPD3), University of Florida , Gainesville, Florida 32610.
  • Norwood VM; Department of Medicinal Chemistry, College of Pharmacy, ‡Department of Molecular Genetics & Microbiology, College of Medicine, and ⊥Center for Natural Products, Drug Discovery and Development (CNPD3), University of Florida , Gainesville, Florida 32610.
  • Kallifidas D; Department of Medicinal Chemistry, College of Pharmacy, ‡Department of Molecular Genetics & Microbiology, College of Medicine, and ⊥Center for Natural Products, Drug Discovery and Development (CNPD3), University of Florida , Gainesville, Florida 32610.
  • Bai F; Department of Medicinal Chemistry, College of Pharmacy, ‡Department of Molecular Genetics & Microbiology, College of Medicine, and ⊥Center for Natural Products, Drug Discovery and Development (CNPD3), University of Florida , Gainesville, Florida 32610.
  • Nguyen MT; Department of Medicinal Chemistry, College of Pharmacy, ‡Department of Molecular Genetics & Microbiology, College of Medicine, and ⊥Center for Natural Products, Drug Discovery and Development (CNPD3), University of Florida , Gainesville, Florida 32610.
  • Rolfe M; Department of Medicinal Chemistry, College of Pharmacy, ‡Department of Molecular Genetics & Microbiology, College of Medicine, and ⊥Center for Natural Products, Drug Discovery and Development (CNPD3), University of Florida , Gainesville, Florida 32610.
  • Burch GM; Department of Medicinal Chemistry, College of Pharmacy, ‡Department of Molecular Genetics & Microbiology, College of Medicine, and ⊥Center for Natural Products, Drug Discovery and Development (CNPD3), University of Florida , Gainesville, Florida 32610.
  • Jin S; Department of Medicinal Chemistry, College of Pharmacy, ‡Department of Molecular Genetics & Microbiology, College of Medicine, and ⊥Center for Natural Products, Drug Discovery and Development (CNPD3), University of Florida , Gainesville, Florida 32610.
  • Luesch H; Department of Medicinal Chemistry, College of Pharmacy, ‡Department of Molecular Genetics & Microbiology, College of Medicine, and ⊥Center for Natural Products, Drug Discovery and Development (CNPD3), University of Florida , Gainesville, Florida 32610.
  • Huigens RW; Department of Medicinal Chemistry, College of Pharmacy, ‡Department of Molecular Genetics & Microbiology, College of Medicine, and ⊥Center for Natural Products, Drug Discovery and Development (CNPD3), University of Florida , Gainesville, Florida 32610.
J Med Chem ; 59(8): 3808-25, 2016 04 28.
Article in En | MEDLINE | ID: mdl-27018907
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Phenazines / Biofilms / Drug Resistance, Bacterial / Halogens / Mycobacterium tuberculosis Limits: Humans Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 2016 Document type: Article Country of publication: United States
Fulltext
Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Phenazines / Biofilms / Drug Resistance, Bacterial / Halogens / Mycobacterium tuberculosis Limits: Humans Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 2016 Document type: Article Country of publication: United States