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Mouse model of chromosome mosaicism reveals lineage-specific depletion of aneuploid cells and normal developmental potential.
Bolton, Helen; Graham, Sarah J L; Van der Aa, Niels; Kumar, Parveen; Theunis, Koen; Fernandez Gallardo, Elia; Voet, Thierry; Zernicka-Goetz, Magdalena.
Affiliation
  • Bolton H; Department of Physiology, Development and Neuroscience and Gurdon Institute, University of Cambridge, Downing Street, Cambridge CB2 3EG, UK.
  • Graham SJL; Department of Physiology, Development and Neuroscience and Gurdon Institute, University of Cambridge, Downing Street, Cambridge CB2 3EG, UK.
  • Van der Aa N; Department of Human Genetics, University of Leuven, KU Leuven, Leuven 3000, Belgium.
  • Kumar P; Department of Human Genetics, University of Leuven, KU Leuven, Leuven 3000, Belgium.
  • Theunis K; Department of Human Genetics, University of Leuven, KU Leuven, Leuven 3000, Belgium.
  • Fernandez Gallardo E; Department of Human Genetics, University of Leuven, KU Leuven, Leuven 3000, Belgium.
  • Voet T; Department of Human Genetics, University of Leuven, KU Leuven, Leuven 3000, Belgium.
  • Zernicka-Goetz M; Sanger Institute-EBI Single-Cell Genomics Centre, Wellcome Trust Sanger Institute, Hinxton CB10 1SA, UK.
Nat Commun ; 7: 11165, 2016 Mar 29.
Article in En | MEDLINE | ID: mdl-27021558
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Blastocyst / Cell Lineage / Aneuploidy / Models, Genetic / Mosaicism Type of study: Prognostic_studies Limits: Animals / Female / Humans / Male Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2016 Document type: Article Affiliation country: United kingdom Country of publication: United kingdom
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Blastocyst / Cell Lineage / Aneuploidy / Models, Genetic / Mosaicism Type of study: Prognostic_studies Limits: Animals / Female / Humans / Male Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2016 Document type: Article Affiliation country: United kingdom Country of publication: United kingdom