Immunoglobulin G4 (IgG4)-associated pouchitis - Part of IgG4 related disease? A case series and review of the literature.
Dig Liver Dis
; 48(7): 817-9, 2016 Jul.
Article
in En
| MEDLINE
| ID: mdl-27038705
ABSTRACT
BACKGROUND AND AIMS:
IgG4-mediated pouchitis was first described in 2011. The aetiology and pathogenesis of IgG4-associated pouchitis is unknown. Over the last four years, less than seventy cases of IgG-associated pouchitis have been reported from a pouchitis clinic in Cleveland.METHODS:
We report the first two cases of IgG4-associated pouchitis from our inflammatory bowel disease clinic and outside of Cleveland.CONCLUSION:
This highlights the fact that this entity could be more common than we think. It is important for general gastroenterologists to think about IgG4-mediated disease if the patient has refractory pouchitis, so early diagnosis and referral can be made. This would avoid the cost of expensive therapy and minimize antibiotic use which is what happened in our cases prior to this diagnosis being made.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Autoimmune Diseases
/
Immunoglobulin G
/
Colitis, Ulcerative
/
Proctocolectomy, Restorative
/
Pouchitis
/
Colonic Pouches
Type of study:
Risk_factors_studies
/
Screening_studies
Limits:
Adult
/
Female
/
Humans
/
Male
/
Middle aged
Language:
En
Journal:
Dig Liver Dis
Journal subject:
GASTROENTEROLOGIA
Year:
2016
Document type:
Article