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An acetylcholine alpha7 positive allosteric modulator rescues a schizophrenia-associated brain endophenotype in the 15q13.3 microdeletion, encompassing CHRNA7.
Gass, Natalia; Weber-Fahr, Wolfgang; Sartorius, Alexander; Becker, Robert; Didriksen, Michael; Stensbøl, Tine Bryan; Bastlund, Jesper Frank; Meyer-Lindenberg, Andreas; Schwarz, Adam J.
Affiliation
  • Gass N; Research Group Translational Imaging, Department of Neuroimaging, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Germany. Electronic address: natalia.gass@zi-mannheim.de.
  • Weber-Fahr W; Research Group Translational Imaging, Department of Neuroimaging, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Germany.
  • Sartorius A; Research Group Translational Imaging, Department of Neuroimaging, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Germany; Department of Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Germa
  • Becker R; Research Group Translational Imaging, Department of Neuroimaging, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Germany.
  • Didriksen M; H. Lundbeck A/S, Valby, Denmark.
  • Stensbøl TB; H. Lundbeck A/S, Valby, Denmark.
  • Bastlund JF; H. Lundbeck A/S, Valby, Denmark.
  • Meyer-Lindenberg A; Department of Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Germany.
  • Schwarz AJ; Tailored Therapeutics - Neuroscience, Eli Lilly and Company, Indianapolis, IN, USA; Department of Psychological and Brain Sciences, Indiana University, Bloomington, IN, USA; Department of Radiology and Imaging Sciences, Indiana University, Indianapolis, IN, USA.
Eur Neuropsychopharmacol ; 26(7): 1150-60, 2016 07.
Article in En | MEDLINE | ID: mdl-27061851
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Schizophrenia / Seizures / Brain / Cholinergic Agents / Chromosome Disorders / Alpha7 Nicotinic Acetylcholine Receptor / Intellectual Disability Type of study: Risk_factors_studies Limits: Animals Language: En Journal: Eur Neuropsychopharmacol Journal subject: PSICOFARMACOLOGIA Year: 2016 Document type: Article Country of publication: Netherlands
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Schizophrenia / Seizures / Brain / Cholinergic Agents / Chromosome Disorders / Alpha7 Nicotinic Acetylcholine Receptor / Intellectual Disability Type of study: Risk_factors_studies Limits: Animals Language: En Journal: Eur Neuropsychopharmacol Journal subject: PSICOFARMACOLOGIA Year: 2016 Document type: Article Country of publication: Netherlands