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A phase I study of binimetinib (MEK162) in Japanese patients with advanced solid tumors.
Watanabe, K; Otsu, S; Hirashima, Y; Morinaga, R; Nishikawa, K; Hisamatsu, Y; Shimokata, T; Inada-Inoue, M; Shibata, T; Takeuchi, H; Watanabe, T; Tokushige, K; Maacke, H; Shiaro, K; Ando, Y.
Affiliation
  • Watanabe K; Department of Medical Oncology, Kouseiren Tsurumi Hospital, 4333 Ooaza Tsurumi, Beppu, Oita, 879-5593, Japan. kwata@me.com.
  • Otsu S; Department of Medical Oncology and Hematology, Oita University Faculty of Medicine, Oita, Japan. kwata@me.com.
  • Hirashima Y; Department of Medical Oncology and Hematology, Oita University Faculty of Medicine, Oita, Japan.
  • Morinaga R; Department of Medical Oncology and Hematology, Oita University Faculty of Medicine, Oita, Japan.
  • Nishikawa K; Department of Medical Oncology and Hematology, Oita University Faculty of Medicine, Oita, Japan.
  • Hisamatsu Y; Department of Medical Oncology and Hematology, Oita University Faculty of Medicine, Oita, Japan.
  • Shimokata T; Department of Medical Oncology and Hematology, Oita University Faculty of Medicine, Oita, Japan.
  • Inada-Inoue M; Department of Clinical Oncology and Chemotherapy, Nagoya University Hospital, Nagoya, Aichi, Japan.
  • Shibata T; Department of Clinical Oncology and Chemotherapy, Nagoya University Hospital, Nagoya, Aichi, Japan.
  • Takeuchi H; Department of Clinical Oncology and Chemotherapy, Nagoya University Hospital, Nagoya, Aichi, Japan.
  • Watanabe T; Oncology Early Clinical Trial Management Department, Novartis Pharma KK, Tokyo, Japan.
  • Tokushige K; Medical Science Liaison Group, Novartis Pharma KK, Tokyo, Japan.
  • Maacke H; Integrated Science and Operations Department, Novartis Pharma KK, Tokyo, Japan.
  • Shiaro K; Translational Clinical Oncology, Novartis Pharma AG, Basel, Switzerland.
  • Ando Y; Department of Medical Oncology and Hematology, Oita University Faculty of Medicine, Oita, Japan.
Cancer Chemother Pharmacol ; 77(6): 1157-64, 2016 06.
Article in En | MEDLINE | ID: mdl-27071922
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Benzimidazoles / MAP Kinase Kinase 1 / MAP Kinase Kinase 2 / Neoplasms / Antineoplastic Agents Limits: Adult / Aged / Female / Humans / Male / Middle aged Country/Region as subject: Asia Language: En Journal: Cancer Chemother Pharmacol Year: 2016 Document type: Article Affiliation country: Japan Country of publication: Germany
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Benzimidazoles / MAP Kinase Kinase 1 / MAP Kinase Kinase 2 / Neoplasms / Antineoplastic Agents Limits: Adult / Aged / Female / Humans / Male / Middle aged Country/Region as subject: Asia Language: En Journal: Cancer Chemother Pharmacol Year: 2016 Document type: Article Affiliation country: Japan Country of publication: Germany