Cigarette Smoke Induces Human Airway Epithelial Senescence via Growth Differentiation Factor 15 Production.

Wu, Qun; Jiang, Di; Matsuda, Jennifer L; Ternyak, Kristina; Zhang, Bicheng; Chu, Hong Wei

Wu, Qun; Jiang, Di; Matsuda, Jennifer L; Ternyak, Kristina; Zhang, Bicheng; Chu, Hong Wei.

Affiliation

Wu Q; 1 Department of Medicine and.
Jiang D; 1 Department of Medicine and.
Matsuda JL; 2 Mouse Genetics Core Facility, National Jewish Health, Denver, Colorado.
Ternyak K; 2 Mouse Genetics Core Facility, National Jewish Health, Denver, Colorado.
Zhang B; 2 Mouse Genetics Core Facility, National Jewish Health, Denver, Colorado.
Chu HW; 1 Department of Medicine and.

Am J Respir Cell Mol Biol ; 55(3): 429-38, 2016 09.

Article in En | MEDLINE | ID: mdl-27093475

Subject(s)

Cellular Senescence; Epithelial Cells/metabolism; Epithelial Cells/pathology; Growth Differentiation Factor 15/biosynthesis; Smoking/adverse effects; Activin Receptors, Type II/metabolism; Aged; CRISPR-Cas Systems/genetics; Gene Knockdown Techniques; Humans; Lung/metabolism; Lung/pathology; Middle Aged; Phosphorylation; Protein Binding; Signal Transduction; Smad1 Protein/metabolism

Key words

airway epithelial cells; cellular senescence; cigarette smoke; growth differentiation factor 15

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Smoking / Cellular Senescence / Epithelial Cells / Growth Differentiation Factor 15 Limits: Aged / Humans / Middle aged Language: En Journal: Am J Respir Cell Mol Biol Journal subject: BIOLOGIA MOLECULAR Year: 2016 Document type: Article Country of publication: United States

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