Magistral drugs in hospitalized newborns and children. / Medicamentos magistrais em recémnascidos e crianças hospitalizados.
Rev Paul Pediatr
; 34(4): 403-407, 2016 Dec.
Article
in En, Pt
| MEDLINE
| ID: mdl-27131897
ABSTRACT
OBJECTIVE:
Study the use of magistral oral solutions and suspensions in infants and children at a university hospital.METHODS:
This is a descriptive study based on the analysis of the assessed hospital's magistral drug request forms regarding the patients in the neonatal ICU, Obstetrics, Pediatrics and Pediatric Emergency from January 2012 to December 2013. The frequency of drug requests and dispensation was evaluated and the consumption of each active ingredient of the preparations was expressed as number of "infant defined daily dose" (iDDD) and of iDDD/100 bed-days.RESULTS:
A total of 657 forms were analyzed - a monthly average of 27 pediatric preparations. The neonatal ICU accounted for 69.6% of these requests. Twenty-one drug items were used, of which the most common were folinic acid (88 requests), sulfadiazine (85) and captopril (73). The consumption of the active principle in these preparations varied in number of iDDD, from 7.5 (hydralazine) to 16,520.0 (folic acid), and in number of iDDD/100 bed-days in the neonatal ICU, from 0.1 (zinc sulfate) to 146.1 (folic acid).CONCLUSIONS:
The constant consumption of magistral oral solutions and suspensions by newborns and children of the assessed hospital indicates the need for such preparations as a pediatric therapeutic alternative in this hospital.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Solutions
/
Suspensions
/
Prescription Drugs
Type of study:
Observational_studies
Limits:
Child
/
Humans
/
Newborn
Language:
En
/
Pt
Journal:
Rev Paul Pediatr
Year:
2016
Document type:
Article
Affiliation country:
Brazil