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Combinatorial targeting of TSLP, IL-25, and IL-33 in type 2 cytokine-driven inflammation and fibrosis.
Vannella, Kevin M; Ramalingam, Thirumalai R; Borthwick, Lee A; Barron, Luke; Hart, Kevin M; Thompson, Robert W; Kindrachuk, Kristen N; Cheever, Allen W; White, Sandra; Budelsky, Alison L; Comeau, Michael R; Smith, Dirk E; Wynn, Thomas A.
Affiliation
  • Vannella KM; Immunopathogenesis Section, Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
  • Ramalingam TR; Immunopathogenesis Section, Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
  • Borthwick LA; Immunopathogenesis Section, Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA. Tissue Fibrosis and Repair Group, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne NE2 4HH, UK.
  • Barron L; Immunopathogenesis Section, Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
  • Hart KM; Immunopathogenesis Section, Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
  • Thompson RW; Immunopathogenesis Section, Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
  • Kindrachuk KN; Immunopathogenesis Section, Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
  • Cheever AW; Immunopathogenesis Section, Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA. Biomedical Research Institute, Rockville, MD 20852, USA.
  • White S; Immunopathogenesis Section, Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
  • Budelsky AL; Department of Inflammation Research, Amgen, 1201 Amgen Court West, Seattle, WA 98119, USA.
  • Comeau MR; Department of Inflammation Research, Amgen, 1201 Amgen Court West, Seattle, WA 98119, USA.
  • Smith DE; Department of Inflammation Research, Amgen, 1201 Amgen Court West, Seattle, WA 98119, USA.
  • Wynn TA; Immunopathogenesis Section, Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA. twynn@niaid.nih.gov.
Sci Transl Med ; 8(337): 337ra65, 2016 05 04.
Article in En | MEDLINE | ID: mdl-27147589
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Fibrosis / Cytokines / Interleukin-17 / Interleukin-33 / Inflammation / Lung Neoplasms Type of study: Prognostic_studies Language: En Journal: Sci Transl Med Journal subject: CIENCIA / MEDICINA Year: 2016 Document type: Article Affiliation country: United States Country of publication: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Fibrosis / Cytokines / Interleukin-17 / Interleukin-33 / Inflammation / Lung Neoplasms Type of study: Prognostic_studies Language: En Journal: Sci Transl Med Journal subject: CIENCIA / MEDICINA Year: 2016 Document type: Article Affiliation country: United States Country of publication: United States