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Biochemical and biophysical characterization of cell-free synthesized Rift Valley fever virus nucleoprotein capsids enables in vitro screening to identify novel antivirals.
Broce, Sean; Hensley, Lisa; Sato, Tomoharu; Lehrer-Graiwer, Joshua; Essrich, Christian; Edwards, Katie J; Pajda, Jacqueline; Davis, Christopher J; Bhadresh, Rami; Hurt, Clarence R; Freeman, Beverly; Lingappa, Vishwanath R; Kelleher, Colm A; Karpuj, Marcela V.
Affiliation
  • Broce S; Prosetta Antiviral Inc, San Francisco, CA, USA.
  • Hensley L; NIAID, Ft Detrick, MD, USA.
  • Sato T; Prosetta Antiviral Inc, San Francisco, CA, USA.
  • Lehrer-Graiwer J; DuPont Industrial Biosciences, Palo Alto, CA, USA.
  • Essrich C; Prosetta Antiviral Inc, San Francisco, CA, USA.
  • Edwards KJ; Global Blood Therapeutics, Inc, Palo Alto, CA, USA.
  • Pajda J; Prosetta Antiviral Inc, San Francisco, CA, USA.
  • Davis CJ; CUBRC, Inc, Buffalo, NY, USA.
  • Bhadresh R; Life Technologies, Inc, Grand Island, NY, USA.
  • Hurt CR; Biomedical Advanced Research & Development Authority, Office of the Assistant Secretary of Preparedness & Response, U.S. Department of Health & Human Services, Washington, DC, USA.
  • Freeman B; Prosetta Antiviral Inc, San Francisco, CA, USA.
  • Lingappa VR; Biocon Bristol-Myers Squibb, Syngene International Ltd, Bangalore, India.
  • Kelleher CA; Prosetta Antiviral Inc, San Francisco, CA, USA.
  • Karpuj MV; Prosetta Antiviral Inc, San Francisco, CA, USA.
Biol Direct ; 11: 25, 2016 05 14.
Article in En | MEDLINE | ID: mdl-27179769

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Antiviral Agents / Rift Valley fever virus / Capsid / Drug Evaluation, Preclinical / Drug Discovery Type of study: Diagnostic_studies / Screening_studies Language: En Journal: Biol Direct Year: 2016 Document type: Article Affiliation country: United States Country of publication: United kingdom

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Antiviral Agents / Rift Valley fever virus / Capsid / Drug Evaluation, Preclinical / Drug Discovery Type of study: Diagnostic_studies / Screening_studies Language: En Journal: Biol Direct Year: 2016 Document type: Article Affiliation country: United States Country of publication: United kingdom