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Abrus Agglutinin, a type II ribosome inactivating protein inhibits Akt/PH domain to induce endoplasmic reticulum stress mediated autophagy-dependent cell death.
Panda, Prashanta Kumar; Behera, Birendra; Meher, Biswa Ranjan; Das, Durgesh Nandini; Mukhopadhyay, Subhadip; Sinha, Niharika; Naik, Prajna Paramita; Roy, Bibhas; Das, Joyjyoti; Paul, Subhankar; Maiti, Tapas K; Agarwal, Rajesh; Bhutia, Sujit K.
Affiliation
  • Panda PK; Department of Life Science, National Institute of Technology, Rourkela, Odisha, India.
  • Behera B; Department of Biotechnology, Indian Institute of Technology, Kharagpur, West Bengal, India.
  • Meher BR; Department of Biochemistry, Indian Institute of Science, Bangalore, Karnataka, India.
  • Das DN; Department of Life Science, National Institute of Technology, Rourkela, Odisha, India.
  • Mukhopadhyay S; Department of Life Science, National Institute of Technology, Rourkela, Odisha, India.
  • Sinha N; Department of Life Science, National Institute of Technology, Rourkela, Odisha, India.
  • Naik PP; Department of Life Science, National Institute of Technology, Rourkela, Odisha, India.
  • Roy B; Department of Biotechnology, Indian Institute of Technology, Kharagpur, West Bengal, India.
  • Das J; Department of Biotechnology, Indian Institute of Technology, Kharagpur, West Bengal, India.
  • Paul S; Department of Biotechnology and Medical Engineering, National Institute of Technology, Rourkela, Odisha, India.
  • Maiti TK; Department of Biotechnology, Indian Institute of Technology, Kharagpur, West Bengal, India.
  • Agarwal R; Department of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, Aurora, Colorado.
  • Bhutia SK; University of Colorado Cancer Center, University of Colorado Denver, Aurora, Colorado.
Mol Carcinog ; 56(2): 389-401, 2017 02.
Article in En | MEDLINE | ID: mdl-27182794
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Autophagy / Plant Lectins / Proto-Oncogene Proteins c-akt / Ribosome Inactivating Proteins, Type 2 / Endoplasmic Reticulum Stress / Pleckstrin Homology Domains / Antineoplastic Agents Type of study: Prognostic_studies Limits: Female / Humans Language: En Journal: Mol Carcinog Journal subject: BIOLOGIA MOLECULAR / NEOPLASIAS Year: 2017 Document type: Article Affiliation country: India Country of publication: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Autophagy / Plant Lectins / Proto-Oncogene Proteins c-akt / Ribosome Inactivating Proteins, Type 2 / Endoplasmic Reticulum Stress / Pleckstrin Homology Domains / Antineoplastic Agents Type of study: Prognostic_studies Limits: Female / Humans Language: En Journal: Mol Carcinog Journal subject: BIOLOGIA MOLECULAR / NEOPLASIAS Year: 2017 Document type: Article Affiliation country: India Country of publication: United States