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Hwang-Heuk-San induces apoptosis in HCT116 human colorectal cancer cells through the ROS-mediated activation of caspases and the inactivation of the PI3K/Akt signaling pathway.
Lee, Moon Hee; Hong, Su-Hyun; Park, Cheol; Kim, Gi-Young; Leem, Sun-Hee; Choi, Sung Hyun; Keum, Young-Sam; Hyun, Jin Won; Kwon, Taeg Kyu; Hong, Sang Hoon; Choi, Yung Hyun.
Affiliation
  • Lee MH; Department of Biochemistry, Dongeui University College of Korean Medicine, Busan 614-052, Republic of Korea.
  • Hong SH; Department of Biochemistry, Dongeui University College of Korean Medicine, Busan 614-052, Republic of Korea.
  • Park C; Department of Molecular Biology, Dongeui University, Busan 614-714, Republic of Korea.
  • Kim GY; Department of Marine Life Sciences, Jeju National University, Jeju 690-756, Republic of Korea.
  • Leem SH; Department of Biological Science, Dong-A University, Busan 604­714, Republic of Korea.
  • Choi SH; Department of Safety and System Management, Korea Lift College, Geochang 670-802, Republic of Korea.
  • Keum YS; College of Pharmacy, Dongguk University, Goyang 410-773, Republic of Korea.
  • Hyun JW; Department of Biochemistry, School of Medicine, Jeju National University, Jeju 609-756, Republic of Korea.
  • Kwon TK; Department of Immunology, School of Medicine, Keimyung University, Daegu 704-701, Republic of Korea.
  • Hong SH; Department of Internal Medicine, Dongeui University College of Korean Medicine, Busan 614-052, Republic of Korea.
  • Choi YH; Department of Biochemistry, Dongeui University College of Korean Medicine, Busan 614-052, Republic of Korea.
Oncol Rep ; 36(1): 205-14, 2016 Jul.
Article in En | MEDLINE | ID: mdl-27221553

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Colorectal Neoplasms / Reactive Oxygen Species / Apoptosis / Caspases / Proto-Oncogene Proteins c-akt / Phosphatidylinositol 3-Kinase / Antineoplastic Agents Type of study: Prognostic_studies Limits: Humans Language: En Journal: Oncol Rep Journal subject: NEOPLASIAS Year: 2016 Document type: Article Country of publication: Greece

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Colorectal Neoplasms / Reactive Oxygen Species / Apoptosis / Caspases / Proto-Oncogene Proteins c-akt / Phosphatidylinositol 3-Kinase / Antineoplastic Agents Type of study: Prognostic_studies Limits: Humans Language: En Journal: Oncol Rep Journal subject: NEOPLASIAS Year: 2016 Document type: Article Country of publication: Greece