Association between seasonal factors and multiple sclerosis.
Eur J Epidemiol
; 31(11): 1081-1089, 2016 11.
Article
in En
| MEDLINE
| ID: mdl-27226079
ABSTRACT
Multiple sclerosis (MS) is a chronic inflammatory disease that affects the central nervous system. MS is causing progressive and relapsing neurological disability, due to demyelination and axonal damage. The etiopathogenesis of MS is poorly understood. A number of environmental factors have been previously suggested, including month of birth, vitamin D levels, smoking and viral infections. Previous studies assessing seasonal variation of relapses in multiple sclerosis have had conflicting results. The aim of this review is to assess the association between seasonal factors and MS, in terms of disease onset, relapses and activity.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Seasons
/
Multiple Sclerosis
Type of study:
Risk_factors_studies
Limits:
Animals
/
Humans
Language:
En
Journal:
Eur J Epidemiol
Journal subject:
EPIDEMIOLOGIA
Year:
2016
Document type:
Article
Affiliation country:
Israel