Novel gene and cellular therapy approaches for treating HIV.

Bhoj, Vijay G; Thibodeaux, Suzanne R; Levine, Bruce L

Bhoj, Vijay G; Thibodeaux, Suzanne R; Levine, Bruce L.

Affiliation

Bhoj VG; Department of Pathology and Laboratory Medicine and Center for Cellular Immunotherapies, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA.
Thibodeaux SR; Department of Pathology and Laboratory Medicine and Center for Cellular Immunotherapies, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA.
Levine BL; Department of Pathology and Laboratory Medicine and Center for Cellular Immunotherapies, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA.

Discov Med ; 21(116): 283-92, 2016 04.

Article in En | MEDLINE | ID: mdl-27232514

Subject(s)

Cell- and Tissue-Based Therapy/methods; Genetic Therapy/methods; HIV Infections/therapy; HIV-1/physiology; T-Lymphocytes/transplantation; Anti-Retroviral Agents/adverse effects; Anti-Retroviral Agents/therapeutic use; CRISPR-Cas Systems/genetics; Cell- and Tissue-Based Therapy/adverse effects; DNA-Binding Proteins/genetics; Drug Resistance, Viral; Endoribonucleases/genetics; Escherichia coli Proteins/genetics; Gene Transfer Techniques; Genetic Therapy/adverse effects; HIV Infections/immunology; HIV-1/drug effects; Humans; Quality of Life; Receptors, CCR5/genetics; Transcription Activator-Like Effector Nucleases/genetics; Transplantation, Autologous/methods; rev Gene Products, Human Immunodeficiency Virus/genetics

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Collection: 01-internacional Database: MEDLINE Main subject: T-Lymphocytes / Genetic Therapy / HIV Infections / HIV-1 / Cell- and Tissue-Based Therapy Aspects: Patient_preference Limits: Humans Language: En Journal: Discov Med Year: 2016 Document type: Article Affiliation country: United States Country of publication: United States

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