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SCF (Fbxl17) ubiquitylation of Sufu regulates Hedgehog signaling and medulloblastoma development.
Raducu, Madalina; Fung, Ella; Serres, Sébastien; Infante, Paola; Barberis, Alessandro; Fischer, Roman; Bristow, Claire; Thézénas, Marie-Laëtitia; Finta, Csaba; Christianson, John C; Buffa, Francesca M; Kessler, Benedikt M; Sibson, Nicola R; Di Marcotullio, Lucia; Toftgård, Rune; D'Angiolella, Vincenzo.
Affiliation
  • Raducu M; Cancer Research UK and Medical Research Council Institute for Radiation Oncology, Department of Oncology, University of Oxford, Oxford, UK.
  • Fung E; Cancer Research UK and Medical Research Council Institute for Radiation Oncology, Department of Oncology, University of Oxford, Oxford, UK.
  • Serres S; Cancer Research UK and Medical Research Council Institute for Radiation Oncology, Department of Oncology, University of Oxford, Oxford, UK.
  • Infante P; Center for Life NanoScience@Sapienza, Istituto Italiano di Tecnologia, Rome, Italy.
  • Barberis A; Cancer Research UK and Medical Research Council Institute for Radiation Oncology, Department of Oncology, University of Oxford, Oxford, UK.
  • Fischer R; Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
  • Bristow C; Cancer Research UK and Medical Research Council Institute for Radiation Oncology, Department of Oncology, University of Oxford, Oxford, UK.
  • Thézénas ML; Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
  • Finta C; Department of Biosciences and Nutrition, Center for Innovative Medicine, Karolinska Institutet, Huddinge, Sweden.
  • Christianson JC; Ludwig Institute for Cancer Research, University of Oxford, Oxford, UK.
  • Buffa FM; Cancer Research UK and Medical Research Council Institute for Radiation Oncology, Department of Oncology, University of Oxford, Oxford, UK.
  • Kessler BM; Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
  • Sibson NR; Cancer Research UK and Medical Research Council Institute for Radiation Oncology, Department of Oncology, University of Oxford, Oxford, UK.
  • Di Marcotullio L; Department of Molecular Medicine, University "La Sapienza", Rome, Italy Pasteur Institute/Cenci Bolognetti Foundation Sapienza University, Rome, Italy.
  • Toftgård R; Department of Biosciences and Nutrition, Center for Innovative Medicine, Karolinska Institutet, Huddinge, Sweden.
  • D'Angiolella V; Cancer Research UK and Medical Research Council Institute for Radiation Oncology, Department of Oncology, University of Oxford, Oxford, UK vincenzo.dangiolella@oncology.ox.ac.uk.
EMBO J ; 35(13): 1400-16, 2016 07 01.
Article in En | MEDLINE | ID: mdl-27234298
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Repressor Proteins / Protein Processing, Post-Translational / F-Box Proteins / Hedgehog Proteins / Medulloblastoma Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: EMBO J Year: 2016 Document type: Article Affiliation country: United kingdom Country of publication: United kingdom
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Repressor Proteins / Protein Processing, Post-Translational / F-Box Proteins / Hedgehog Proteins / Medulloblastoma Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: EMBO J Year: 2016 Document type: Article Affiliation country: United kingdom Country of publication: United kingdom