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Quantification of vosaroxin and its metabolites N-desmethylvosaroxin and O-desmethylvosaroxin in human plasma and urine using high-performance liquid chromatography-tandem mass spectrometry.
Nijenhuis, C M; Lucas, L; Rosing, H; Jamieson, G; Fox, J A; Schellens, J H M; Beijnen, J H.
Affiliation
  • Nijenhuis CM; Department of Pharmacy & Pharmacology, Antoni van Leeuwenhoek/The Netherlands Cancer Institute and MC Slotervaart, Amsterdam, The Netherlands. Electronic address: Cynthia.Nijenhuis@slz.nl.
  • Lucas L; Department of Pharmacy & Pharmacology, Antoni van Leeuwenhoek/The Netherlands Cancer Institute and MC Slotervaart, Amsterdam, The Netherlands.
  • Rosing H; Department of Pharmacy & Pharmacology, Antoni van Leeuwenhoek/The Netherlands Cancer Institute and MC Slotervaart, Amsterdam, The Netherlands.
  • Jamieson G; Sunesis Pharmaceuticals, Inc. South San Francisco, CA, United States.
  • Fox JA; Sunesis Pharmaceuticals, Inc. South San Francisco, CA, United States.
  • Schellens JH; Division of Clinical Pharmacology, Department of Medical Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands; Division of Pharmacoepidemiology and Clinical Pharmacology, Faculty of Science, Department of Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands.
  • Beijnen JH; Department of Pharmacy & Pharmacology, Antoni van Leeuwenhoek/The Netherlands Cancer Institute and MC Slotervaart, Amsterdam, The Netherlands; Division of Pharmacoepidemiology and Clinical Pharmacology, Faculty of Science, Department of Pharmaceutical Sciences, Utrecht University, Utrecht, The N
Article in En | MEDLINE | ID: mdl-27236532

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Thiazoles / Chromatography, High Pressure Liquid / Tandem Mass Spectrometry / Naphthyridines / Antineoplastic Agents Limits: Humans Language: En Journal: J Chromatogr B Analyt Technol Biomed Life Sci Journal subject: ENGENHARIA BIOMEDICA Year: 2016 Document type: Article Country of publication: Netherlands

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Thiazoles / Chromatography, High Pressure Liquid / Tandem Mass Spectrometry / Naphthyridines / Antineoplastic Agents Limits: Humans Language: En Journal: J Chromatogr B Analyt Technol Biomed Life Sci Journal subject: ENGENHARIA BIOMEDICA Year: 2016 Document type: Article Country of publication: Netherlands