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Rhomboid intramembrane protease RHBDL4 triggers ER-export and non-canonical secretion of membrane-anchored TGFα.
Wunderle, Lina; Knopf, Julia D; Kühnle, Nathalie; Morlé, Aymeric; Hehn, Beate; Adrain, Colin; Strisovsky, Kvido; Freeman, Matthew; Lemberg, Marius K.
Affiliation
  • Wunderle L; Zentrum für Molekulare Biologie der Universität Heidelberg (ZMBH), DKFZ-ZMBH Allianz, Im Neuenheimer Feld 282, 69120 Heidelberg, Germany.
  • Knopf JD; Zentrum für Molekulare Biologie der Universität Heidelberg (ZMBH), DKFZ-ZMBH Allianz, Im Neuenheimer Feld 282, 69120 Heidelberg, Germany.
  • Kühnle N; Zentrum für Molekulare Biologie der Universität Heidelberg (ZMBH), DKFZ-ZMBH Allianz, Im Neuenheimer Feld 282, 69120 Heidelberg, Germany.
  • Morlé A; Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Prague, Czech Republic.
  • Hehn B; Zentrum für Molekulare Biologie der Universität Heidelberg (ZMBH), DKFZ-ZMBH Allianz, Im Neuenheimer Feld 282, 69120 Heidelberg, Germany.
  • Adrain C; Instituto Gulbenkian de Ciência, Rua da Quinta Grande, 6, 2780-156, Oeiras, Portugal.
  • Strisovsky K; Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Prague, Czech Republic.
  • Freeman M; Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford OX1 3RE, UK.
  • Lemberg MK; Zentrum für Molekulare Biologie der Universität Heidelberg (ZMBH), DKFZ-ZMBH Allianz, Im Neuenheimer Feld 282, 69120 Heidelberg, Germany.
Sci Rep ; 6: 27342, 2016 06 06.
Article in En | MEDLINE | ID: mdl-27264103
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Transforming Growth Factor alpha / Endoplasmic Reticulum / Exosomes / Golgi Apparatus / Membrane Proteins Type of study: Prognostic_studies Limits: Animals Language: En Journal: Sci Rep Year: 2016 Document type: Article Affiliation country: Germany Country of publication: United kingdom
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Transforming Growth Factor alpha / Endoplasmic Reticulum / Exosomes / Golgi Apparatus / Membrane Proteins Type of study: Prognostic_studies Limits: Animals Language: En Journal: Sci Rep Year: 2016 Document type: Article Affiliation country: Germany Country of publication: United kingdom