Scalable procedure for the fragmentation of hydroperoxides mediated by copper and iron tetrafluoroborate salts.
Org Biomol Chem
; 14(26): 6197-200, 2016 Jul 14.
Article
in En
| MEDLINE
| ID: mdl-27273761
ABSTRACT
An improved protocol for the formal elimination of propene from organic substrates is reported. This process entails the ozonolytic conversion of an alkene to a methoxy hydroperoxide which undergoes fragmentation mediated by copper and iron. The use of soluble Cu(BF4)2 and Fe(BF4)2 results in reproducible results up to a 100 gram scale.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Language:
En
Journal:
Org Biomol Chem
Journal subject:
BIOQUIMICA
/
QUIMICA
Year:
2016
Document type:
Article
Affiliation country:
United States