C5L2, the Second C5a Anaphylatoxin Receptor, Suppresses LPS-Induced Acute Lung Injury.

Wang, Ruobing; Lu, Bao; Gerard, Craig; Gerard, Norma P

Wang, Ruobing; Lu, Bao; Gerard, Craig; Gerard, Norma P.

Affiliation

Wang R; 1 Division of Respiratory Diseases, Boston Children's Hospital, Boston, Massachusetts.
Lu B; 2 Department of Medicine, Harvard Medical School, Boston, Massachusetts; and.
Gerard C; 1 Division of Respiratory Diseases, Boston Children's Hospital, Boston, Massachusetts.
Gerard NP; 1 Division of Respiratory Diseases, Boston Children's Hospital, Boston, Massachusetts.

Am J Respir Cell Mol Biol ; 55(5): 657-666, 2016 11.

Article in En | MEDLINE | ID: mdl-27285858

Subject(s)

Acute Lung Injury/metabolism; Acute Lung Injury/pathology; Receptors, Chemokine/metabolism; Acute Lung Injury/genetics; Acute Lung Injury/physiopathology; Administration, Intranasal; Animals; Bronchoalveolar Lavage Fluid; Chemokines/genetics; Chemokines/metabolism; Edema/complications; Edema/pathology; Edema/physiopathology; Gene Expression Regulation; Hemorrhage/complications; Hemorrhage/pathology; Hemorrhage/physiopathology; Inflammation Mediators/metabolism; Lipopolysaccharides/administration & dosage; Lung/pathology; Mice, Inbred BALB C; Neutrophils/metabolism; Peroxidase/metabolism; Receptor, Anaphylatoxin C5a; Receptors, Chemokine/antagonists & inhibitors; Receptors, Chemokine/deficiency; Respiratory Mechanics; Toll-Like Receptors/genetics; Toll-Like Receptors/metabolism

Key words

C5L2; C5a anaphylatoxin; LPS; acute lung injury

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Receptors, Chemokine / Acute Lung Injury Limits: Animals Language: En Journal: Am J Respir Cell Mol Biol Journal subject: BIOLOGIA MOLECULAR Year: 2016 Document type: Article Country of publication: United States

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